Study on the interaction of metal ions in active center of nuclease P1 with CoCl2
文献类型：期刊论文
| 作者 | Zheng, XF; Chi, NY; Zhang, QF; Yuan, YL; Li, XY; Hu, JH |
| 刊名 | chinese journal of inorganic chemistry
 |
| 出版日期 | 2003-04-01 |
| 卷号 | 19期号:4页码:377-380 |
| 关键词 | nuclease P1 CoCl2 NMR interaction |
| 英文摘要 | the paper using various ways, such as icp, vis, nmr and measurement of enzyme activity, extensively study the direct interaction of nuclease p1 with inorganic metal. compound (cocl2) . it has been found that in aqueous solution, there exists a direct interaction between the metal ions of the active center in the metalloenzyme (nuclease pi) and external added cocl2. as a result, part of the metal ions in metalloenzyme were substituted and the corresponding metalloenzyme derivatives were produced and the catalytic activity of enzyme were changed, and the h-1 nmr spectrum of co (11)-substituted nuclease pi derivative of co (11) in zn2 site of active center was firstly obtained. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, inorganic & nuclear |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | penicillium-citrinum ; crystal-structure ; specificity ; resolution |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000182036800008 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/138352]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Dalian Univ Technol, Coll Bioengn, Dalian 116622, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zheng, XF,Chi, NY,Zhang, QF,et al. Study on the interaction of metal ions in active center of nuclease P1 with CoCl2[J]. chinese journal of inorganic chemistry,2003,19(4):377-380. |
| APA | Zheng, XF,Chi, NY,Zhang, QF,Yuan, YL,Li, XY,&Hu, JH.(2003).Study on the interaction of metal ions in active center of nuclease P1 with CoCl2.chinese journal of inorganic chemistry,19(4),377-380. |
| MLA | Zheng, XF,et al."Study on the interaction of metal ions in active center of nuclease P1 with CoCl2".chinese journal of inorganic chemistry 19.4(2003):377-380. |
入库方式： OAI收割
来源：大连化学物理研究所
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