Optical resolution of alpha-alkyl phenyl acetonitriles by HPLC on cellulose triacetate chiral stationary phases coated on underivatized silica gel
文献类型：期刊论文
| 作者 | Chen, XM; Zou, HF; Yang, LI; Wang, HL; Zhang, Q |
| 刊名 | chirality
 |
| 出版日期 | 2000 |
| 卷号 | 12期号:8页码:621-626 |
| 关键词 | coating solvent effect organic modifiers mass distribution of cellulose chiral recognition mechanism optical resolution alpha-alkyl phenyl acetonitriles |
| 英文摘要 | microcrystalline celluloses from two sources were used to prepare cellulose triacetate chiral stationary phases (csps) coated on underivatized silica gel, which shows discriminating chiral recognition for enantiomers. the chiral separation of four or-alkyl phenyl acetonitriles was investigated on the prepared csps. it was observed that the concentration of the coating solvent of phenol in dichloromethane plays an important role in the resolution of the solutes. a series of primary alcohols, including secondary and tertiary alcohols, were used as mobile phase modifiers to investigate the effect of the structures of these modifiers on the capacity factors (k') and the separation factors (alpha). also, the effect of the concentration of alcohol on the capacity factors and separation factors was examined. the chiral recognition mechanism of alpha-alkyl phenyl acetonitriles on the prepared csps is discussed. (c) 2000 wiley-liss, inc. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | chemistry, medicinal ; chemistry, analytical ; chemistry, organic ; pharmacology & pharmacy |
| 研究领域[WOS] | pharmacology & pharmacy ; chemistry |
| 关键词[WOS] | performance liquid-chromatography ; derivatives ; enantiomers ; triacetylcellulose ; recognition ; retention ; mechanism |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000088277900004 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/138728]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Natl Chromatograph R&D Ctr, Dalian Inst Chem Phys, Dalian 116011, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, XM,Zou, HF,Yang, LI,et al. Optical resolution of alpha-alkyl phenyl acetonitriles by HPLC on cellulose triacetate chiral stationary phases coated on underivatized silica gel[J]. chirality,2000,12(8):621-626. |
| APA | Chen, XM,Zou, HF,Yang, LI,Wang, HL,&Zhang, Q.(2000).Optical resolution of alpha-alkyl phenyl acetonitriles by HPLC on cellulose triacetate chiral stationary phases coated on underivatized silica gel.chirality,12(8),621-626. |
| MLA | Chen, XM,et al."Optical resolution of alpha-alkyl phenyl acetonitriles by HPLC on cellulose triacetate chiral stationary phases coated on underivatized silica gel".chirality 12.8(2000):621-626. |
入库方式： OAI收割
来源：大连化学物理研究所
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