Desorption-ionization mass spectrometry with porous silica gel and its derivatives as matrix
文献类型：期刊论文
| 作者 | Zhang, QC; Zou, HF; Guo, Z; Chen, XM; Jiang, HH; Ni, JY |
| 刊名 | chemical journal of chinese universities-chinese
 |
| 出版日期 | 2001-10-01 |
| 卷号 | 22期号:10页码:1637-1640 |
| 关键词 | silica gel matrix desorption-ionization mass spectrometry immobilization of matrix small molecule analysis |
| 英文摘要 | porous silica gel and its derivatives have been applied as matrix for the analysis of small molecules. in contrast to the conventional maldi-tof ms, the signal interference of low-molecular analytes by the matrix has been eliminated in the maldi-tof ms with porous silica gel and its derivatives as the matrix. the detection of limit by this method reached the fetomole levels, and almost no fragment of the analytes has been observed. the porous structure of silica gel is essential for effective desorption and ionization of the analytes. among several different types of silica gel, the silica gel with the pore size of 30 nm gives the best signal. the analyte penetration into the pore is very important. matrix agents of dhb and cca have been covalently bound to silica gel for the improvement of the intensity of the spectrum signal. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, multidisciplinary |
| 研究领域[WOS] | chemistry |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000172051000007 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/138992]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Analyt Ctr, Dalian 116011, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, QC,Zou, HF,Guo, Z,et al. Desorption-ionization mass spectrometry with porous silica gel and its derivatives as matrix[J]. chemical journal of chinese universities-chinese,2001,22(10):1637-1640. |
| APA | Zhang, QC,Zou, HF,Guo, Z,Chen, XM,Jiang, HH,&Ni, JY.(2001).Desorption-ionization mass spectrometry with porous silica gel and its derivatives as matrix.chemical journal of chinese universities-chinese,22(10),1637-1640. |
| MLA | Zhang, QC,et al."Desorption-ionization mass spectrometry with porous silica gel and its derivatives as matrix".chemical journal of chinese universities-chinese 22.10(2001):1637-1640. |
入库方式： OAI收割
来源：大连化学物理研究所
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