Chiral separation of lobeline and benzhexol by capillary electrophoresis using the reaction mixture of beta-cyclodextrin, phosphorous-pentoxide and L-glutamic acid as chiral selector
文献类型：期刊论文
| 作者 | Lin, XL; Li, GB; Jiang, WQ; Chu, YB; Wu, P; Yafeng, G |
| 刊名 | analytica chimica acta
 |
| 出版日期 | 2001-03-08 |
| 卷号 | 431期号:1页码:41-48 |
| 关键词 | chiral separation drug lobeline benzhexol capillary electrophoresis |
| 英文摘要 | the reaction mixture of beta -cyclodextrin, phosphorous-pentoxide and l-glutamic acid was successfully used as chiral selector in capillary zone electrophoresis. the reaction process and the main properties of the reaction mixture was introduced in detail. the enantiomeric separation of lobeline and benzhexol were investigated. the chiral resolution was strongly influenced by the concentration of the reaction mixture, ph and the organic modifier. the two compounds studied can be enantiomerically resolved with a high resolution for lobeline (rs = 2.37) and benzhexol (rs = 2.60) in less than 14 min with no capillary treatment. a possible separation mechanism and several factors influencing the chiral separation were discussed. (c) 2001 elsevier science b.v. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | zone electrophoresis ; enantiomers ; chromatography ; resolution ; additives |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000167571700004 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/138998]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Shangdong Inst Light Ind, Dept Chem Engn, Jinan 250100, Peoples R China 2.Dalian Inst Chem Phys, Dalian 116012, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lin, XL,Li, GB,Jiang, WQ,et al. Chiral separation of lobeline and benzhexol by capillary electrophoresis using the reaction mixture of beta-cyclodextrin, phosphorous-pentoxide and L-glutamic acid as chiral selector[J]. analytica chimica acta,2001,431(1):41-48. |
| APA | Lin, XL,Li, GB,Jiang, WQ,Chu, YB,Wu, P,&Yafeng, G.(2001).Chiral separation of lobeline and benzhexol by capillary electrophoresis using the reaction mixture of beta-cyclodextrin, phosphorous-pentoxide and L-glutamic acid as chiral selector.analytica chimica acta,431(1),41-48. |
| MLA | Lin, XL,et al."Chiral separation of lobeline and benzhexol by capillary electrophoresis using the reaction mixture of beta-cyclodextrin, phosphorous-pentoxide and L-glutamic acid as chiral selector".analytica chimica acta 431.1(2001):41-48. |
入库方式： OAI收割
来源：大连化学物理研究所
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