Enantiomer separation by strong anion-exchange capillary electrochromatography with dynamically modified sulfated beta-cyclodextrin
文献类型：期刊论文
| 作者 | Ye, ML; Zou, HF; Lei, ZD; Wu, RN; Liu, Z; Ni, JY |
| 刊名 | electrophoresis
 |
| 出版日期 | 2001-02-01 |
| 卷号 | 22期号:3页码:518-525 |
| 关键词 | enantiomer separation electrochromatography strong anion-exchange stationary phase dynamically modified stationary phase sulfated beta-cyclodextrin |
| 英文摘要 | a novel mode of capillary electrochromatography (ceg) based on a dynamically modified stationary phase was presented for chiral separation. the capillary column was packed with strong anion-exchange (sax) stationary phase packing; the sulfated beta -cyclodextrin (s-cd), which was added to the mobile phase, was dynamically adsorbed to the packing surface. separation of enantiomers was achieved by their different abilities to farm an inclusion complex with the adsorbed s-cd. the enantiomers of tryptophan, praziquantel, atropine, metoprolol, and verapamil were successfully separated in this system with a column efficiency of 36000-412000 plates/m. the resolution value obtained for atropine was as high as 11.23. the superiority of cec with a dynamically modified stationary phase over that with a physically adsorbed stationary phase was demonstrated. the influence of ionic strength, s-cd concentration, and methanol content on separation was also studied. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | modified cationic surfactant ; chiral stationary-phase ; ion-exchange ; electrophoresis ; selectivity ; column |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000167362400023 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/139017]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ye, ML,Zou, HF,Lei, ZD,et al. Enantiomer separation by strong anion-exchange capillary electrochromatography with dynamically modified sulfated beta-cyclodextrin[J]. electrophoresis,2001,22(3):518-525. |
| APA | Ye, ML,Zou, HF,Lei, ZD,Wu, RN,Liu, Z,&Ni, JY.(2001).Enantiomer separation by strong anion-exchange capillary electrochromatography with dynamically modified sulfated beta-cyclodextrin.electrophoresis,22(3),518-525. |
| MLA | Ye, ML,et al."Enantiomer separation by strong anion-exchange capillary electrochromatography with dynamically modified sulfated beta-cyclodextrin".electrophoresis 22.3(2001):518-525. |
入库方式： OAI收割
来源：大连化学物理研究所
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