The multicriteria-decision-making simultaneous optimization based on genetic algorithm in chiral capillary electrophoresis separation
文献类型：期刊论文
| 作者 | Xiong, JH; Zhang, PD; Shi, XZ; Zhang, YK; Xu, GW |
| 刊名 | chemical journal of chinese universities-chinese
 |
| 出版日期 | 2004-05-01 |
| 卷号 | 25期号:5页码:896-899 |
| 关键词 | capillary electrophoresis genetic algorithm desirability function enantiomer separation multicritiria optimization |
| 英文摘要 | a methodology based on the combination of desirability function approach and genetic algorithm was applied to the multicriteria-decision-making simultaneous optimization of epinephrine enantiomers by capillary electrophoresis. uniform design, an experimental design method, was employed to examine how the factors such as electrolyte concentration, ph, concentration of chiral selector and voltage affected resolution, analysis time and peak height. in order to achieve the simultaneous optimization of the three goals for efficient, fast and highly sensitive separation, the derringer desirability functions were tested. the real-value encoded genetic algorithm was used to achieve the search for maximizing desirability and several optimal separation conditions were obtained. under the optimized conditions, the values of total desirability functions were increased by 10.4% in comparison to those under the optimal condition defined by the uniform design experiment. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, multidisciplinary |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | enantiomeric separation ; chromatography |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000221514700028 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/139291]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xiong, JH,Zhang, PD,Shi, XZ,et al. The multicriteria-decision-making simultaneous optimization based on genetic algorithm in chiral capillary electrophoresis separation[J]. chemical journal of chinese universities-chinese,2004,25(5):896-899. |
| APA | Xiong, JH,Zhang, PD,Shi, XZ,Zhang, YK,&Xu, GW.(2004).The multicriteria-decision-making simultaneous optimization based on genetic algorithm in chiral capillary electrophoresis separation.chemical journal of chinese universities-chinese,25(5),896-899. |
| MLA | Xiong, JH,et al."The multicriteria-decision-making simultaneous optimization based on genetic algorithm in chiral capillary electrophoresis separation".chemical journal of chinese universities-chinese 25.5(2004):896-899. |
入库方式： OAI收割
来源：大连化学物理研究所
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