Investigation of norvancomycin chiral stationary phase for the enantioseparation of derived amino acids on reversed phase conditions
文献类型：期刊论文
| 作者 | Ding, GS; Cong, RZ; Wang, J |
| 刊名 | chinese journal of analytical chemistry
 |
| 出版日期 | 2004-05-01 |
| 卷号 | 32期号:5页码:606-610 |
| 关键词 | norwancomycin chiral stationary phase high performance liquid chromatography chiral separation dansyl-amino acids |
| 英文摘要 | using the newly synthesized norvancomycin chiral stationary phase (nvc-csp), the enantiomers of dansyl-alpha-amino-n-butyric acid (dns-but), dansyl-methionine (dns-met) dansyl-threonine (dns-thr) and dansyl-glutamic acid (dns-glu) were directly separated on reversed phase conditions. the influences of some chromatographic parameters, such as ph of buffer, the content of organic modifier, temperature and flow rate, were evaluated, and furthermore, the possible mechanism of chiral discrimination was discussed. it was found experimentally that hydrophobic, as well as ionic interactions were important for solute's retention and enantioselectivity in this chromatographic system, and the chiral recognition mechanism was similar to that of protein-based csps. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | macrocyclic antibiotics ; liquid-chromatography ; teicoplanin ; selectors |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000221785200012 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/139339]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116012, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ding, GS,Cong, RZ,Wang, J. Investigation of norvancomycin chiral stationary phase for the enantioseparation of derived amino acids on reversed phase conditions[J]. chinese journal of analytical chemistry,2004,32(5):606-610. |
| APA | Ding, GS,Cong, RZ,&Wang, J.(2004).Investigation of norvancomycin chiral stationary phase for the enantioseparation of derived amino acids on reversed phase conditions.chinese journal of analytical chemistry,32(5),606-610. |
| MLA | Ding, GS,et al."Investigation of norvancomycin chiral stationary phase for the enantioseparation of derived amino acids on reversed phase conditions".chinese journal of analytical chemistry 32.5(2004):606-610. |
入库方式： OAI收割
来源：大连化学物理研究所
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