Facile synthesis of enantiopure 1,1 '-spirobiindane-7,7 '-diol and its 4,4 '-derivatives: Application in enantioselective addition of diethylzinc to aromatic aldehydes
文献类型：期刊论文
| 作者 | Li, ZA; Liang, XM; Wan, BS; Wu, F |
| 刊名 | synthesis-stuttgart
 |
| 出版日期 | 2004-12-01 |
| 期号 | 17页码:2805-2808 |
| 关键词 | alkylations aldehydes stereoselectivity spiro compounds enantiomeric resolution protecting groups |
| 英文摘要 | the enantiopure 1,1'-spirobiindane-7,7'-diol (spinol) and its 4,4'-derivatives 4,4'-diiodo-1,1'-spirobiindane-7,7'-dioi (dispinol) and 4,4'-dimethyl-1, 1'-spirobiindane-7,7'-diol (dmspinol) have been synthesized effectively via (1s)-(-)-4,4'-dibromo-1,1'-spirobiindane-7,7'-diyl bismenthyl carbonate with buli following the cleavage of the bismenthyl carbonate. their absolute configurations were assigned by chemical correlation. they are also applied in the form of their ti-alkoxides as catalysts for the addition of diethylzinc to aldehydes. the addition reactions proceeded with high conversions and enantioselectivities up to 88%. the effect of substitution of the substrate was studied. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, organic |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | chiral spiro phosphoramidites ; asymmetric hydrogenation ; carbonyl-compounds ; ligands ; resolution ; complex ; efficient ; reagents ; alcohols |
| 收录类别 | SCI ; IC ; CCR |
| 语种 | 英语 |
| WOS记录号 | WOS:000225611400005 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/139505]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, ZA,Liang, XM,Wan, BS,et al. Facile synthesis of enantiopure 1,1 '-spirobiindane-7,7 '-diol and its 4,4 '-derivatives: Application in enantioselective addition of diethylzinc to aromatic aldehydes[J]. synthesis-stuttgart,2004(17):2805-2808. |
| APA | Li, ZA,Liang, XM,Wan, BS,&Wu, F.(2004).Facile synthesis of enantiopure 1,1 '-spirobiindane-7,7 '-diol and its 4,4 '-derivatives: Application in enantioselective addition of diethylzinc to aromatic aldehydes.synthesis-stuttgart(17),2805-2808. |
| MLA | Li, ZA,et al."Facile synthesis of enantiopure 1,1 '-spirobiindane-7,7 '-diol and its 4,4 '-derivatives: Application in enantioselective addition of diethylzinc to aromatic aldehydes".synthesis-stuttgart .17(2004):2805-2808. |
入库方式： OAI收割
来源：大连化学物理研究所
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