Preparation of a positively charged cellulose derivative chiral stationary phase with copolymerization reaction for capillary electrochromatographic separation of enantiomers
文献类型：期刊论文
| 作者 | Chen, XM; Qin, F; Liu, YQ; Kong, L; Zou, HF |
| 刊名 | electrophoresis
 |
| 出版日期 | 2004-08-01 |
| 卷号 | 25期号:16页码:2817-2824 |
| 关键词 | capillary electrochromatography cellulose derivative chiral stationary phase copolymerization reaction enantiomeric resolution |
| 英文摘要 | a positively charged chiral stationary phase (csp) was prepared by chemically immobilizing cellulose 3,5-dimethylphenylcarbamate onto methacryloyldiethylenetriaminopropylated silica (mcdeaps) via a radical copolymerization reaction. the prepared csp was evaluated for enantiomer separation in nonaqueous capillary electrochromatography (cec). electroosmotic flow (eof) generated on the prepared csp could be significantly improved with introduction of positive charges into the csp and separation of enantiomers in cec has been achieved with mobile phases of ethanol and hexane-ethanol, respectively. in addition, we investigated the solvent versatility of the immobilized csp on enantioseparations in cec and capillary liquid chromatography (clc) due to the elimination of dissolution of chiral selector in a number of solvents. chiral resolution of some enantiomers was improved by adopting tetrahydrofuran (thf) and chloroform as mobile-phase modifiers, respectively. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | performance liquid-chromatography ; silica-gel ; polysaccharide derivatives ; enantioseparations ; size ; pharmaceuticals ; pore |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000223713000021 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/139545]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatograph Res & Anal Ctr, Dalian 116011, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, XM,Qin, F,Liu, YQ,et al. Preparation of a positively charged cellulose derivative chiral stationary phase with copolymerization reaction for capillary electrochromatographic separation of enantiomers[J]. electrophoresis,2004,25(16):2817-2824. |
| APA | Chen, XM,Qin, F,Liu, YQ,Kong, L,&Zou, HF.(2004).Preparation of a positively charged cellulose derivative chiral stationary phase with copolymerization reaction for capillary electrochromatographic separation of enantiomers.electrophoresis,25(16),2817-2824. |
| MLA | Chen, XM,et al."Preparation of a positively charged cellulose derivative chiral stationary phase with copolymerization reaction for capillary electrochromatographic separation of enantiomers".electrophoresis 25.16(2004):2817-2824. |
入库方式： OAI收割
来源：大连化学物理研究所
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