Interaction between domoic acid and double-stranded oligodeoxy-nucleotide studied by using microchip-based non-gel sieving electrophoresis
文献类型：期刊论文
| 作者 | Zhou, XM; Li, DZ; Shen, Z; Liu, W; Li, GR; Lin, BC |
| 刊名 | chemical journal of chinese universities-chinese
 |
| 出版日期 | 2005-07-10 |
| 卷号 | 26期号:7页码:1252-1254 |
| 关键词 | microchip non-sieving electrophoresis interaction domoic acid 18-mer dsDNA |
| 英文摘要 | the interaction between domoic acid(da) and 18-mer double-stranded dna(dsdna) was investigated by using microchip-based non-gel sieving electrophoresis. for the 18-mer dsdna with a sequence of 3-gcattggttgacgttgca-5', the amount of free dsdna decreases with the increase of the added da and also with the increase of reactive time. meanwhile, the newly-produced two peaks were observed. the experimental results show that there is a strong interaction between da and the 18-mer dsdna. da makes the degradation of the 18-mer dsdna. the non-gel sieving electrophoresis on microchip is a rapid, convenient, highly sensitive method for studying the interaction between dna and small molecules. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, multidisciplinary |
| 研究领域[WOS] | chemistry |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000230753000016 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/139625]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Guangzhou First Municipal Peoples Hosp, Guangzhou Med Coll, Dept Clin Lab, Guangzhou 510500, Guangdong, Peoples R China 3.Dalian Customs Lab, Dalian 116001, Peoples R China 4.Dalian Med Univ, Affiliated Hosp 2, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, XM,Li, DZ,Shen, Z,et al. Interaction between domoic acid and double-stranded oligodeoxy-nucleotide studied by using microchip-based non-gel sieving electrophoresis[J]. chemical journal of chinese universities-chinese,2005,26(7):1252-1254. |
| APA | Zhou, XM,Li, DZ,Shen, Z,Liu, W,Li, GR,&Lin, BC.(2005).Interaction between domoic acid and double-stranded oligodeoxy-nucleotide studied by using microchip-based non-gel sieving electrophoresis.chemical journal of chinese universities-chinese,26(7),1252-1254. |
| MLA | Zhou, XM,et al."Interaction between domoic acid and double-stranded oligodeoxy-nucleotide studied by using microchip-based non-gel sieving electrophoresis".chemical journal of chinese universities-chinese 26.7(2005):1252-1254. |
入库方式： OAI收割
来源：大连化学物理研究所
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