Base effect and inhibition of catalytic activity in palladium-catalyzed N-heteroarylation of pyrazoles with 2,6-dibromopyridine
文献类型：期刊论文
| 作者 | Sun, XJ; Yu, ZK; Wu, SH; Xiao, WJ |
| 刊名 | organometallics
 |
| 出版日期 | 2005-06-06 |
| 卷号 | 24期号:12页码:2959-2963 |
| 英文摘要 | using the catalytic system pd(oac)(2)/pph3, coupling of 2,6-dibromopyridine (1) and pyrazoles (2) in a molar ratio of 1:2:base = 1:2.4:2.5 afforded the monosubstituted compounds 3 as the major products when kotbu was used as the base. without using the catalyst or using naotbu as the base the disubstituted compounds 4 were formed as the major products in yields up to 93%. reactions of 1 and 2 in a molar ratio of 1:2:base = 1:1:1 selectively produced compounds 3 in yields up to 82% when kotbu was used as the base. the complex from the reaction of 3 and pd(oac)(2) did not undergo further reaction with 1 to form 4 in the presence of a base. the base effect and inhibition of catalytic activity for pd(oac)(2) are discussed. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, inorganic & nuclear ; chemistry, organic |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | nitrogen bond formation ; aryl halides ; metal-complexes ; c-n ; arylation ; amination ; chemistry ; ligands ; arylamines ; heteroatom |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000229574600017 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/139634]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide, Wuhan 430007, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, XJ,Yu, ZK,Wu, SH,et al. Base effect and inhibition of catalytic activity in palladium-catalyzed N-heteroarylation of pyrazoles with 2,6-dibromopyridine[J]. organometallics,2005,24(12):2959-2963. |
| APA | Sun, XJ,Yu, ZK,Wu, SH,&Xiao, WJ.(2005).Base effect and inhibition of catalytic activity in palladium-catalyzed N-heteroarylation of pyrazoles with 2,6-dibromopyridine.organometallics,24(12),2959-2963. |
| MLA | Sun, XJ,et al."Base effect and inhibition of catalytic activity in palladium-catalyzed N-heteroarylation of pyrazoles with 2,6-dibromopyridine".organometallics 24.12(2005):2959-2963. |
入库方式： OAI收割
来源：大连化学物理研究所
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