中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Multicriteria-decision-making simultaneous optimization independent of statistical models in chiral capillary electrophoresis separation

文献类型:期刊论文

作者Xiong, JH; Weng, QF; Yuan, KL; Zhang, YK; Xu, GW
刊名chinese journal of analytical chemistry
出版日期2005-06-01
卷号33期号:6页码:755-758
关键词capillary electrophoresis optimization genetic algorithm uniform design desirability function
英文摘要considering the complexity of chiral capillary electrophoresis separation mechanism, a multicriteria-decision-making optimization approach based on binary-coded genetic algorithm, which was independent of the statistic model used, was developed. according to the experiment parameters and their importances, the initial experiments were arranged using a uniform design. in order to achieve the simultaneous optimization of the two major electrophoretic performance goals for efficient and fast separations, the derringer desirability functions were chosen as the optimization criteriaon. the selected parameters were encoded into binary bit strings, and then genetic algorithm calculations were performed to generate a new set of experimental conditions by the values of total desirability functions. this cycle process was repeated until a best separation criterion was reached. the method proposed was successfully applied to the enantioseparation of warfarin by chiral capillary electrophoresis.
WOS标题词science & technology ; physical sciences
类目[WOS]chemistry, analytical
研究领域[WOS]chemistry
关键词[WOS]beta-cyclodextrin ; zone-electrophoresis ; acids
收录类别SCI
语种英语
WOS记录号WOS:000230362500003
公开日期2015-11-10
源URL[http://159.226.238.44/handle/321008/139663]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
作者单位Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714
Xiong, JH,Weng, QF,Yuan, KL,et al. Multicriteria-decision-making simultaneous optimization independent of statistical models in chiral capillary electrophoresis separation[J]. chinese journal of analytical chemistry,2005,33(6):755-758.
APA Xiong, JH,Weng, QF,Yuan, KL,Zhang, YK,&Xu, GW.(2005).Multicriteria-decision-making simultaneous optimization independent of statistical models in chiral capillary electrophoresis separation.chinese journal of analytical chemistry,33(6),755-758.
MLA Xiong, JH,et al."Multicriteria-decision-making simultaneous optimization independent of statistical models in chiral capillary electrophoresis separation".chinese journal of analytical chemistry 33.6(2005):755-758.

入库方式: OAI收割

来源:大连化学物理研究所

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