Multicriteria-decision-making simultaneous optimization independent of statistical models in chiral capillary electrophoresis separation
文献类型:期刊论文
作者 | Xiong, JH; Weng, QF; Yuan, KL; Zhang, YK; Xu, GW |
刊名 | chinese journal of analytical chemistry
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出版日期 | 2005-06-01 |
卷号 | 33期号:6页码:755-758 |
关键词 | capillary electrophoresis optimization genetic algorithm uniform design desirability function |
英文摘要 | considering the complexity of chiral capillary electrophoresis separation mechanism, a multicriteria-decision-making optimization approach based on binary-coded genetic algorithm, which was independent of the statistic model used, was developed. according to the experiment parameters and their importances, the initial experiments were arranged using a uniform design. in order to achieve the simultaneous optimization of the two major electrophoretic performance goals for efficient and fast separations, the derringer desirability functions were chosen as the optimization criteriaon. the selected parameters were encoded into binary bit strings, and then genetic algorithm calculations were performed to generate a new set of experimental conditions by the values of total desirability functions. this cycle process was repeated until a best separation criterion was reached. the method proposed was successfully applied to the enantioseparation of warfarin by chiral capillary electrophoresis. |
WOS标题词 | science & technology ; physical sciences |
类目[WOS] | chemistry, analytical |
研究领域[WOS] | chemistry |
关键词[WOS] | beta-cyclodextrin ; zone-electrophoresis ; acids |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000230362500003 |
公开日期 | 2015-11-10 |
源URL | [http://159.226.238.44/handle/321008/139663] ![]() |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian 116023, Peoples R China |
推荐引用方式 GB/T 7714 | Xiong, JH,Weng, QF,Yuan, KL,et al. Multicriteria-decision-making simultaneous optimization independent of statistical models in chiral capillary electrophoresis separation[J]. chinese journal of analytical chemistry,2005,33(6):755-758. |
APA | Xiong, JH,Weng, QF,Yuan, KL,Zhang, YK,&Xu, GW.(2005).Multicriteria-decision-making simultaneous optimization independent of statistical models in chiral capillary electrophoresis separation.chinese journal of analytical chemistry,33(6),755-758. |
MLA | Xiong, JH,et al."Multicriteria-decision-making simultaneous optimization independent of statistical models in chiral capillary electrophoresis separation".chinese journal of analytical chemistry 33.6(2005):755-758. |
入库方式: OAI收割
来源:大连化学物理研究所
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