Reversal of enantioselectivity by adding Ti(O-i Pr)(4): novel sulfamide-amine alcohol ligands for the catalytic asymmetric addition of diethylzinc to aldehydes
文献类型：期刊论文
| 作者 | Mao, JC; Wan, BS; Zhang, ZJ; Wang, RL; Wu, F; Lu, SW |
| 刊名 | journal of molecular catalysis a-chemical
 |
| 出版日期 | 2005-01-04 |
| 卷号 | 225期号:1页码:33-37 |
| 关键词 | sulfamide-amine alcohol catalytic asymmetric addition diethylzinc reversal of enantioselectivity aldehyde |
| 英文摘要 | novel sulfamide-amine alcohol ligands (6) derived from (-)-ephedrine (4a) and (+)-pseudoephedrine (4b) with multiple stereogenic centers were applied to the catalytic asymmetric addition of diethylzinc to aldehydes, providing (s)-products in high yields and good enantioselectivities. these sulfamide-amine alcohols together with ti((opr)-pr-i)(4) were shown to obtain the (r)-products in significant enantiomeric excesses (e.e.) and high yields. in addition, sulfamide-amine alcohols were superior to the original chiral sources 4a and 4b, which afforded no enantioselectivity in the ti((opr)-pr-i)(4) -mediated reaction. (c) 2004 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, physical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | n-tosyl aziridines ; crystal-structures ; pyridyl alcohols ; benzaldehyde ; origin ; dialkylzincs ; dimethylzinc ; derivatives ; alkylation ; ketones |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000226180300007 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/139767]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Mao, JC,Wan, BS,Zhang, ZJ,et al. Reversal of enantioselectivity by adding Ti(O-i Pr)(4): novel sulfamide-amine alcohol ligands for the catalytic asymmetric addition of diethylzinc to aldehydes[J]. journal of molecular catalysis a-chemical,2005,225(1):33-37. |
| APA | Mao, JC,Wan, BS,Zhang, ZJ,Wang, RL,Wu, F,&Lu, SW.(2005).Reversal of enantioselectivity by adding Ti(O-i Pr)(4): novel sulfamide-amine alcohol ligands for the catalytic asymmetric addition of diethylzinc to aldehydes.journal of molecular catalysis a-chemical,225(1),33-37. |
| MLA | Mao, JC,et al."Reversal of enantioselectivity by adding Ti(O-i Pr)(4): novel sulfamide-amine alcohol ligands for the catalytic asymmetric addition of diethylzinc to aldehydes".journal of molecular catalysis a-chemical 225.1(2005):33-37. |
入库方式： OAI收割
来源：大连化学物理研究所
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