In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms
文献类型：期刊论文
| 作者 | Zhang, CZ; Wang, SX; Zhang, Y; Chen, JP; Liang, XM |
| 刊名 | journal of ethnopharmacology
 |
| 出版日期 | 2005-04-26 |
| 卷号 | 98期号:3页码:295-300 |
| 关键词 | phytoestrogens hormone replacement therapy Chinese medicine Saccharomyces cerevisiae |
| 英文摘要 | the estrogenic activity of 70% etoh extracts of 32 traditional chinese medicinal plants, selected according to their reported efficacy for the treatment of menopausal symptoms, was assessed using a recombinant yeast system with both a human estrogen receptor expression plasmid and a reporter plasmid. among them, 11 (34%) species proved to be active. polygonum to cuspidatum had the highest estrogenic relative potency (rp) (3.28 x 10(-3)), followed by rheum palmatum (3.85 x 10(-4)), cassia obtusifolio (3.49 x 10(-4)), polygonum multiflorum (2.87 x 10(-4)), epimedium brevicormum (2.30 x 10(-4)), psoralea corylifolia (1.90 x 10(-4)), cynomorium songaricum (1.78 x 10(-4)), belamcanda chinensis (1.26 x 10(-4)). scutellaria baicalensis (8.77 x 10(-5)), astragalus membranaceus (8.47 x 10(-5)) and puerario lobata (6.17 x 10(-5)). the ec50 value of 17 beta-estradiol used as the positive control was 0.205 +/- 0.025 ng/ml (rp = 100). this study gave support to the reported efficacy of chinese medicines used for hormone replacement therapy. (c) 2005 elsevier ireland ltd. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine |
| 类目[WOS] | plant sciences ; chemistry, medicinal ; integrative & complementary medicine ; pharmacology & pharmacy |
| 研究领域[WOS] | plant sciences ; pharmacology & pharmacy ; integrative & complementary medicine |
| 关键词[WOS] | saccharomyces-cerevisiae ; yeast ; phytoestrogens ; receptor ; screen |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000228688300010 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/139781]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116011, Peoples R China 2.Coll Bio & Food Technol, Dalian Inst Light Ind, Dalian 116034, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, CZ,Wang, SX,Zhang, Y,et al. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms[J]. journal of ethnopharmacology,2005,98(3):295-300. |
| APA | Zhang, CZ,Wang, SX,Zhang, Y,Chen, JP,&Liang, XM.(2005).In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms.journal of ethnopharmacology,98(3),295-300. |
| MLA | Zhang, CZ,et al."In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms".journal of ethnopharmacology 98.3(2005):295-300. |
入库方式： OAI收割
来源：大连化学物理研究所
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