Chiral separation of 1,1 '-bi-2-naphthol and its analogue on molecular imprinting monolithic columns by HPLC
文献类型：期刊论文
| 作者 | Ou, JJ; Tang, SW; Zou, HF |
| 刊名 | journal of separation science
 |
| 出版日期 | 2005-11-01 |
| 卷号 | 28期号:17页码:2282-2287 |
| 关键词 | 1 chiral separation molecular imprinting polymer monolithic column 5 1 '-bi-2-naphthol 5 ' 6 6 ' 7 7 ' 8 8 '-octahydro-1 1 '-bi-2-naphthol |
| 英文摘要 | two molecular imprinting polymer (mip) monolithic columns with (s)-(-)-1,1'-bi-2-naphthol and (r)-(+)-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthol as the templating molecules, respectively, have been prepared by in situ polymerization using 4-vinylpyridine and ethylene dimethacrylate as functional monomer and cross-linker, respectively. the columns with good flow-through properties were obtained by changing the molar ratio of the functional monomer and the template molecule. the effects of mobile-phase composition on separation of enantiomers were systematically investigated. the results indicate that hydrophobic interaction in aqueous solution and hydrogen-bonding interaction in acn between the enantiomers and polymers could play important roles in the retention and resolution. the effects of chromatographic conditions, such as flow rate, column temperature, sample loading, on the enantioseparation were also studied. further, these two mip columns show a cross-reactivity. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | capillary electrochromatography ; enantiomer separation ; stationary phases ; mobile phases ; polymers ; recognition ; selectivity ; diastereomers ; resolution ; retention |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000233679200007 |
| 公开日期 | 2015-11-10 |
| 源URL | [http://159.226.238.44/handle/321008/139914]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Ctr, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ou, JJ,Tang, SW,Zou, HF. Chiral separation of 1,1 '-bi-2-naphthol and its analogue on molecular imprinting monolithic columns by HPLC[J]. journal of separation science,2005,28(17):2282-2287. |
| APA | Ou, JJ,Tang, SW,&Zou, HF.(2005).Chiral separation of 1,1 '-bi-2-naphthol and its analogue on molecular imprinting monolithic columns by HPLC.journal of separation science,28(17),2282-2287. |
| MLA | Ou, JJ,et al."Chiral separation of 1,1 '-bi-2-naphthol and its analogue on molecular imprinting monolithic columns by HPLC".journal of separation science 28.17(2005):2282-2287. |
入库方式： OAI收割
来源：大连化学物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。