Quantitative investigation of the interaction between granulocyte-macrophage colonystimulating factor and heparin by capillary zone ellectrophoresis
文献类型：期刊论文
| 作者 | Liang, Aiye; Du, Yuguang; Wang, Keyi; Lin, Bingcheng |
| 刊名 | journal of separation science
 |
| 出版日期 | 2006-07-01 |
| 卷号 | 29期号:11页码:1637-1641 |
| 关键词 | capillary zone electrophoresis granulocyte-macrophage colony-stimulating factor heparin interaction |
| 英文摘要 | the interactions between granulocyte-macrophage colony-stimulating factor (gmcsf) and heparin or low-molecular weight heparin (lmwh) were studied by cze. it was found that gm-csf could bind to both heparin and lmwh. the binding constants were calculated from scatchard regression to be (6.5 +/- 0.8) x 10(5)/m and (11.2 +/- 0.7) x 10(5)/m, respectively. the specificity of the interaction between gm-csf and heparin was also studied by employing another sulfated k carrageenan oligosaccharide as a control. results showed that k carrageenan oligosaccharide could not interact with gm-csf, indicating that gm-csf could specifically interact with heparin. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | colony-stimulating factor ; factor gm-csf ; electrophoresis ; binding ; glycosaminoglycans ; affinity ; sulfate |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000239574100014 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/139942]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China 3.Chinese Acad Sci, Shanghai Acad Life Sci, Inst Biochem & Cell Biol, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liang, Aiye,Du, Yuguang,Wang, Keyi,et al. Quantitative investigation of the interaction between granulocyte-macrophage colonystimulating factor and heparin by capillary zone ellectrophoresis[J]. journal of separation science,2006,29(11):1637-1641. |
| APA | Liang, Aiye,Du, Yuguang,Wang, Keyi,&Lin, Bingcheng.(2006).Quantitative investigation of the interaction between granulocyte-macrophage colonystimulating factor and heparin by capillary zone ellectrophoresis.journal of separation science,29(11),1637-1641. |
| MLA | Liang, Aiye,et al."Quantitative investigation of the interaction between granulocyte-macrophage colonystimulating factor and heparin by capillary zone ellectrophoresis".journal of separation science 29.11(2006):1637-1641. |
入库方式： OAI收割
来源：大连化学物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。