Site-selective DNA cleavage by a novel complex of copper-conjugate of Phen and polyamide containing N-methylimidazole rings
文献类型:期刊论文
作者 | Liu, Dan; Zhou, Jiang; Li, Huihui; Zheng, Bo; Yuan, Gu |
刊名 | bioorganic & medicinal chemistry letters
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出版日期 | 2006-10-01 |
卷号 | 16期号:19页码:5032-5035 |
关键词 | DNA cleaving activity ESI-mass spectrometry site-selective DNA cleavage |
英文摘要 | a novel conjugate of 3-clip-phen and polyamide containing three n-methylimidazole (im) rings was synthesized for the targeting human telomeric repeat of 5'-ttaggg-3', and the dna cleaving activity and the sequence selectivity of the complex of copper-conjugate were confirmed by electrospray ionization mass spectrometry. (c) 2006 elsevier ltd. all rights reserved. |
WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
类目[WOS] | chemistry, medicinal ; chemistry, organic |
研究领域[WOS] | pharmacology & pharmacy ; chemistry |
关键词[WOS] | telomerase activity ; binding ; cancer ; cells |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000240615400010 |
公开日期 | 2015-11-17 |
源URL | [http://159.226.238.44/handle/321008/140061] ![]() |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | 1.Peking Univ, Beijing Natl Lab Mol Sci, Key Lab Bioorgan Chem & Mol Engn, Minist Educ,Dept Chem Biol,Coll Chem & Mol Engn, Beijing 100871, Peoples R China 2.Peking Univ, Proteom Lab, Med & Hlth Analyt Ctr, Beijing 100083, Peoples R China |
推荐引用方式 GB/T 7714 | Liu, Dan,Zhou, Jiang,Li, Huihui,et al. Site-selective DNA cleavage by a novel complex of copper-conjugate of Phen and polyamide containing N-methylimidazole rings[J]. bioorganic & medicinal chemistry letters,2006,16(19):5032-5035. |
APA | Liu, Dan,Zhou, Jiang,Li, Huihui,Zheng, Bo,&Yuan, Gu.(2006).Site-selective DNA cleavage by a novel complex of copper-conjugate of Phen and polyamide containing N-methylimidazole rings.bioorganic & medicinal chemistry letters,16(19),5032-5035. |
MLA | Liu, Dan,et al."Site-selective DNA cleavage by a novel complex of copper-conjugate of Phen and polyamide containing N-methylimidazole rings".bioorganic & medicinal chemistry letters 16.19(2006):5032-5035. |
入库方式: OAI收割
来源:大连化学物理研究所
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