Investigation of the concentration dependence of mass transfer coefficients in reversed-phase liquid chromatography
文献类型：期刊论文
| 作者 | Hao, Weiqiang; Wang, Junde; Zhang, Xiangmin |
| 刊名 | journal of separation science
 |
| 出版日期 | 2006-12-01 |
| 卷号 | 29期号:18页码:2745-2758 |
| 关键词 | caffeine chromatographic models frontal analysis reversed-phase liquid chromatography surface diffusivity |
| 英文摘要 | in order to investigate the concentration dependence of mass transfer coefficients in rplc, experimental breakthrough curves obtained by staircase frontal analysis (fa) were fitted to the simplified models such as multiplate (mp) model, equilibrium dispersive (ed) model, and transport model, and the sophisticated models such as lumped pore diffusion (por) model and general rate (gr) model. the nip model was used to obtain the initial guesses of the parameters of the ed and the transport models. then the best values were obtained by minimizing the differences between theoretical and experimental values with a nonlinear fitting procedure. the values of the parameters of the por and the gr models can be calculated by using the expressions derived from the plate height equations, which was further validated by using the fitting method. it was found that the mass transfer coefficients would depend on the solute concentration. this can be ascribed to the surface diffusivity, which correlates with the concentration and is lumped into the mass transfer coefficients for both simplified and sophisticated models. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | bovine serum-albumin ; anion-exchange chromatography ; frontal analysis ; transfer kinetics ; band profiles ; nonlinear chromatography ; affinity-chromatography ; 1-indanol enantiomers ; cellulose triacetate ; peak asymmetry |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000243338800006 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/140167]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hao, Weiqiang,Wang, Junde,Zhang, Xiangmin. Investigation of the concentration dependence of mass transfer coefficients in reversed-phase liquid chromatography[J]. journal of separation science,2006,29(18):2745-2758. |
| APA | Hao, Weiqiang,Wang, Junde,&Zhang, Xiangmin.(2006).Investigation of the concentration dependence of mass transfer coefficients in reversed-phase liquid chromatography.journal of separation science,29(18),2745-2758. |
| MLA | Hao, Weiqiang,et al."Investigation of the concentration dependence of mass transfer coefficients in reversed-phase liquid chromatography".journal of separation science 29.18(2006):2745-2758. |
入库方式： OAI收割
来源：大连化学物理研究所
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