Study of conical columns with 10 degrees opening angle for preparative liquid chromatography
文献类型：期刊论文
| 作者 | Guan, WN; Xu, F; Tan, F; Guan, YF |
| 刊名 | journal of chromatography a
 |
| 出版日期 | 2006-03-10 |
| 卷号 | 1108期号:2页码:218-224 |
| 关键词 | preparative liquid chromatography conical column column scale up sample loadability |
| 英文摘要 | the efficiency and sample capacity of conical liquid chromatographic columns with 10 degrees opening angle were studied at different ratio of cross section areas of inlet to outlet (a(in)/a(out)) and column dimension. as the a(in)/a(out) ratio changed from 4 to 2.25, the reduced plate height (h) was reduced and the h value decreased 12% when the column dimension was scaled up proportionally because of relatively smaller dead volume on both end of the column. compared to cylindrical columns having corresponding lengths and volumes, the conical columns with 10 degrees opening angle were superior in column efficiency, resolution and the maximum peak concentration at column outlet; the loadability of conical column was improved 30-40% on injection volume and 50-60% on sample mass, respectively, over cylindrical columns. (c) 2006 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | performance ; purification ; efficiency ; scale ; peaks ; flow |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000235854900010 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/140329]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Dept Analyt Chem & Microinstrumentat, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guan, WN,Xu, F,Tan, F,et al. Study of conical columns with 10 degrees opening angle for preparative liquid chromatography[J]. journal of chromatography a,2006,1108(2):218-224. |
| APA | Guan, WN,Xu, F,Tan, F,&Guan, YF.(2006).Study of conical columns with 10 degrees opening angle for preparative liquid chromatography.journal of chromatography a,1108(2),218-224. |
| MLA | Guan, WN,et al."Study of conical columns with 10 degrees opening angle for preparative liquid chromatography".journal of chromatography a 1108.2(2006):218-224. |
入库方式： OAI收割
来源：大连化学物理研究所
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