中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Diffusion of acetic acid across oil/water interface in emulsification-internal gelation process for preparation of alginate gel beads

文献类型:期刊论文

作者Xiu-dong, Liu; Wei-ting, Yu; Jun-zhang, Lin; Xiao-jun, Ma; Quan, Yuan
刊名chemical research in chinese universities
出版日期2007-09-01
卷号23期号:5页码:579-584
关键词emulsification-internal gelation technology alginate gel bead diffusion rate constant diffusion coefficient
英文摘要alginate has been widely used in cell microencapsulation and drug delivery systems in the form of gel beads or microcapsules. although an alternative novel emulsification-internal gelation technology has been established and both the properties and the potential applications of the beads in drug delivery systems have been studied, the mechanism has not been well understood compared with the traditional droplet method( external gelation technology). on the basis of our previous knowledge that the novel technology is composed of complicatedly consecutive processes with multistep diffusion and reaction, and the diffusion of acetic acid across oil/water interface being the prerequisite that determines the occurrence and rate for the reactions and the structures and properties of final produced gel beads, a special emphasis was placed on the diffusion process. with the aid of diffusion modeling and simple experimental design, the diffusion rate constant and diffusion coefficient of acetic acid across oil/water interface were determined to be in the orders of magnitude of 10(-6) and 10(-16), respectively. this knowledge will be of particular importance in understanding and interpreting the formation, structure of the gel beads and the relationship between the structure and properties and guiding the preparation and quality control of the gel beads.
WOS标题词science & technology ; physical sciences
类目[WOS]chemistry, multidisciplinary
研究领域[WOS]chemistry
关键词[WOS]calcium alginate ; chitosan ; microencapsulation ; microcapsules ; microspheres ; release ; behavior ; dna
收录类别SCI
语种英语
WOS记录号WOS:000250324000021
公开日期2015-11-17
源URL[http://159.226.238.44/handle/321008/140591]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Biomed Mat Engn, Dalian 116023, Peoples R China
2.Dalian Univ, Coll Environm & Chem Engn, Dalian 116622, Peoples R China
推荐引用方式
GB/T 7714
Xiu-dong, Liu,Wei-ting, Yu,Jun-zhang, Lin,et al. Diffusion of acetic acid across oil/water interface in emulsification-internal gelation process for preparation of alginate gel beads[J]. chemical research in chinese universities,2007,23(5):579-584.
APA Xiu-dong, Liu,Wei-ting, Yu,Jun-zhang, Lin,Xiao-jun, Ma,&Quan, Yuan.(2007).Diffusion of acetic acid across oil/water interface in emulsification-internal gelation process for preparation of alginate gel beads.chemical research in chinese universities,23(5),579-584.
MLA Xiu-dong, Liu,et al."Diffusion of acetic acid across oil/water interface in emulsification-internal gelation process for preparation of alginate gel beads".chemical research in chinese universities 23.5(2007):579-584.

入库方式: OAI收割

来源:大连化学物理研究所

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