DNA-mediated charge transport by minor groove-binding polyamide
文献类型:期刊论文
作者 | Ji, Zhonghua; Li, Jingjian; Zhu, Bin; Yuan, Gu; Cai, Shengmin |
刊名 | electrochemistry communications
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出版日期 | 2007-07-01 |
卷号 | 9期号:7页码:1667-1671 |
关键词 | polyamide DNA minor groove charge transport broadened pi-stack human telomere |
英文摘要 | a novel polyamide-modified electrode was fabricated successfully by surface synthesis. the dna-mediated charge transport by minor groove-binding polyamide was observed for the first time with a [ru(nh3)(6)](2+/3+) probe. two control experiments on hsc11h22nh2 sam/au electrode, with and without dna adsorption, confirmed that polyamide-dna complex was a medium of charge transport. four different dna sequences were employed to investigate the effect of the charge transport of the polyamide-dna complex in the minor groove. the peak current and a positive shift of peak potential were enhanced with the affinity increase between polyamide and dna sequences. the experimental result offers a powerful tool for exquisite recognition of different sequences of base-pairs in double-stranded dna. (c) 2007 elsevier b.v. all rights reserved. |
WOS标题词 | science & technology ; physical sciences |
类目[WOS] | electrochemistry |
研究领域[WOS] | electrochemistry |
关键词[WOS] | hairpin polyamide ; modified surfaces ; electron-transfer ; structural basis ; base-pairs ; recognition ; sequence ; motif ; gold ; electrochemistry |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000248089400046 |
公开日期 | 2015-11-17 |
源URL | [http://159.226.238.44/handle/321008/140698] ![]() |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | 1.Peking Univ, Coll Chem & Mol Engn, Inst Chem Phys, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China 2.Peking Univ, Minist Educ, Dept Biol Chem, Key Lab Bioinorgan Chem & Mol Engn, Beijing 100871, Peoples R China |
推荐引用方式 GB/T 7714 | Ji, Zhonghua,Li, Jingjian,Zhu, Bin,et al. DNA-mediated charge transport by minor groove-binding polyamide[J]. electrochemistry communications,2007,9(7):1667-1671. |
APA | Ji, Zhonghua,Li, Jingjian,Zhu, Bin,Yuan, Gu,&Cai, Shengmin.(2007).DNA-mediated charge transport by minor groove-binding polyamide.electrochemistry communications,9(7),1667-1671. |
MLA | Ji, Zhonghua,et al."DNA-mediated charge transport by minor groove-binding polyamide".electrochemistry communications 9.7(2007):1667-1671. |
入库方式: OAI收割
来源:大连化学物理研究所
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