Synthesis and activity of the photoaffinity-labeled functional probe based on prenyl side-chain
文献类型：期刊论文
| 作者 | Li Ling-Dong; Tang Wei; Liu Wu-Jun; Zhao Zong-Bao |
| 刊名 | chinese journal of organic chemistry
 |
| 出版日期 | 2008-03-01 |
| 卷号 | 28期号:3页码:489-493 |
| 关键词 | prenyl side-chain functional probe photoaffinity labeling chemical proteomics |
| 英文摘要 | a novel functional probe bearing both a benzophenone moiety and a biotin moiety was synthesized in 5 steps with an overall yield of 9%. photoaffinity labeling and biotin blot experiment with the probe and the crude protein extracts from saccharomyces cerevisiae as 2.399 revealed that the synthetic probe was attached to a number of proteins, providing a basis for further chemical proteomics research. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, organic |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | protein farnesyltransferase ; farnesyl transferase ; diphosphate analogs ; chemical strategies ; prenyltransferases ; inhibitors ; proteomics ; reagents |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000254422500023 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/140786]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li Ling-Dong,Tang Wei,Liu Wu-Jun,et al. Synthesis and activity of the photoaffinity-labeled functional probe based on prenyl side-chain[J]. chinese journal of organic chemistry,2008,28(3):489-493. |
| APA | Li Ling-Dong,Tang Wei,Liu Wu-Jun,&Zhao Zong-Bao.(2008).Synthesis and activity of the photoaffinity-labeled functional probe based on prenyl side-chain.chinese journal of organic chemistry,28(3),489-493. |
| MLA | Li Ling-Dong,et al."Synthesis and activity of the photoaffinity-labeled functional probe based on prenyl side-chain".chinese journal of organic chemistry 28.3(2008):489-493. |
入库方式： OAI收割
来源：大连化学物理研究所
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