Polyacrylamide-based monolithic capillary column with coating of cellulose tris(3,5-dimethylphenyl-carbamate) for enantiomer separation in capillary electrochromatography
文献类型：期刊论文
| 作者 | Dong, Xiaoli1,2; Wu, Ren'an1; Dong, Jing1; Wu, Minghuo1; Zhu, Yan2; Zou, Hanfa1 |
| 刊名 | electrophoresis
 |
| 出版日期 | 2008-02-01 |
| 卷号 | 29期号:4页码:919-927 |
| 关键词 | capillary electrochromatography cellulose tris(3 enantioseparation polyacrylamide monolithic capillary column 5-dimethylphenyl-carbamate) |
| 英文摘要 | a hydrophilic chiral capillary monolithic column for enantiomer separation in cec was prepared by coating cellulose tris(3,5-dimethylphenyl-carbamate) (cdmpc) on porous hydrophilic poly(acrylamide-co-n,n'-methylene-bisacrylamide) (poly(aa-co-mba)) monolithic matrix with confine of a fused-silica capillary. the coating conditions were optimized to obtain a stable and reproducible chiral stationary phase for cec. the effect of organic modifier of acn in aqueous mobile phase for the enantiomer separation by cec was investigated, and the significant influence of acn on the enantioresolution and electrochromatographic retention was observed. twelve pairs of enantiomers including acidic, neutral, and basic analytes were tested and nine pairs of them were baseline-enantioresolved with acidic and basic aqueous mobile phases. a good within-column repeatability in retention time (rsd = 2.4%) and resolution (rsd = 3.2%) was obtained by consecutive injections of a neutral compound, benzoin, on a prepared chiral monolithic column, while the between-column repeatability in retention time (rsd = 6.4%) and resolution (rsd = 9.6%) was observed by column-to-column examination. the prepared monolithic stationary phase showed good stability in either acidic or basic mobile phase. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | chiral stationary-phase ; performance liquid-chromatography ; polymerization conditions ; porous properties ; continuous beds ; human serum ; enantioseparations ; gels ; tris(3,5-dichlorophenylcarbamate) ; copolymerization |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000253575200021 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/140796]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China 2.Zhejiang Univ, Dept Chem, Hangzhou, Peoples R China |
| 推荐引用方式 GB/T 7714 | Dong, Xiaoli,Wu, Ren'an,Dong, Jing,et al. Polyacrylamide-based monolithic capillary column with coating of cellulose tris(3,5-dimethylphenyl-carbamate) for enantiomer separation in capillary electrochromatography[J]. electrophoresis,2008,29(4):919-927. |
| APA | Dong, Xiaoli,Wu, Ren'an,Dong, Jing,Wu, Minghuo,Zhu, Yan,&Zou, Hanfa.(2008).Polyacrylamide-based monolithic capillary column with coating of cellulose tris(3,5-dimethylphenyl-carbamate) for enantiomer separation in capillary electrochromatography.electrophoresis,29(4),919-927. |
| MLA | Dong, Xiaoli,et al."Polyacrylamide-based monolithic capillary column with coating of cellulose tris(3,5-dimethylphenyl-carbamate) for enantiomer separation in capillary electrochromatography".electrophoresis 29.4(2008):919-927. |
入库方式： OAI收割
来源：大连化学物理研究所
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