Two-dimensional LC-MS analysis of components in Swertia franchetiana Smith
文献类型：期刊论文
| 作者 | Liu, Yanming; Xu, Qing; Xue, Xingya; Zhang, Feifang; Liang, Xinmiao |
| 刊名 | journal of separation science
 |
| 出版日期 | 2008-04-01 |
| 卷号 | 31期号:6-7页码:935-944 |
| 关键词 | mass spectrometry on-column focusing Swertia franchetiana Smith traditional Chinese medicine two-dimensional liquid chromatography |
| 英文摘要 | an off-line 2-d-lc approach was developed for the separation and identification of components in extracts of swertia franchetiana smith, which is a traditional chinese medicine. an octadecylsilica column was used for further separation of fractions from a cyano column with uv and ms detection. in this method, a longer column was used in the second dimension to improve the separation ability, and "on-column focusing" was adopted to reduce sample loss and pollution on concentrating the fractions from the first dimension. more than 118 and 575 components were detected in the chloroform and n-butanol extracts by this method, respectively. in contrast, only 20 and 95 peaks were detected by the one-dimensional method. most of the additionally detected compounds were of low-abundance components. many compounds can be preliminarily identified according to their uv and mass spectra in the two-dimensional method. the obtained results not only demonstrated the powerful resolution of 2-d-lc, but also led to in-depth comprehension of the uv and mass spectra of complex samples. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | performance liquid-chromatography ; traditional chinese medicines ; mass-spectrometry ; reversed-phase ; gas-chromatography ; automated instrumentation ; column ; hplc ; separation ; online |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000255613800005 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/140839]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Grad Sch, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Yanming,Xu, Qing,Xue, Xingya,et al. Two-dimensional LC-MS analysis of components in Swertia franchetiana Smith[J]. journal of separation science,2008,31(6-7):935-944. |
| APA | Liu, Yanming,Xu, Qing,Xue, Xingya,Zhang, Feifang,&Liang, Xinmiao.(2008).Two-dimensional LC-MS analysis of components in Swertia franchetiana Smith.journal of separation science,31(6-7),935-944. |
| MLA | Liu, Yanming,et al."Two-dimensional LC-MS analysis of components in Swertia franchetiana Smith".journal of separation science 31.6-7(2008):935-944. |
入库方式： OAI收割
来源：大连化学物理研究所
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