Efficient enzymatic regioselective benzoylation of 5-fluorouridine catalysed by Novozym 435
文献类型：期刊论文
| 作者 | Wu, Jian1,2; Zong, Min-Hua1; Wu, Hong1; Lou, Wen-Yong1 |
| 刊名 | journal of chemical technology and biotechnology
 |
| 出版日期 | 2008-06-01 |
| 卷号 | 83期号:6页码:814-820 |
| 关键词 | Novozym 435 regioselective acylation 5-fluorouridine 5'-O-benzoyl-5-fluorouridine vinyl benzoate co-solvent |
| 英文摘要 | background: this work focuses on developing a mild, efficient and regioselective enzymatic procedure to synthesise 5'-o-benzoyl-5-fluorouridine, a more powerful antitumour drug than 5-fluorouridine itself, and examining the influences of several key variables on the reaction. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences ; technology |
| 类目[WOS] | biotechnology & applied microbiology ; chemistry, multidisciplinary ; engineering, chemical |
| 研究领域[WOS] | biotechnology & applied microbiology ; chemistry ; engineering |
| 关键词[WOS] | organic-solvents ; water activity ; antitumor-activity ; nonaqueous media ; lipase ; nucleosides ; derivatives ; acylation ; mild ; 1-beta-d-arabinofuranosylcytosine |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000256203400007 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/140972]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.S China Univ Technol, Lab Appl Biocatalysis, Guangzhou 510640, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Catalysis, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Jian,Zong, Min-Hua,Wu, Hong,et al. Efficient enzymatic regioselective benzoylation of 5-fluorouridine catalysed by Novozym 435[J]. journal of chemical technology and biotechnology,2008,83(6):814-820. |
| APA | Wu, Jian,Zong, Min-Hua,Wu, Hong,&Lou, Wen-Yong.(2008).Efficient enzymatic regioselective benzoylation of 5-fluorouridine catalysed by Novozym 435.journal of chemical technology and biotechnology,83(6),814-820. |
| MLA | Wu, Jian,et al."Efficient enzymatic regioselective benzoylation of 5-fluorouridine catalysed by Novozym 435".journal of chemical technology and biotechnology 83.6(2008):814-820. |
入库方式： OAI收割
来源：大连化学物理研究所
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