Protein-responsive imprinted polymers with specific shrinking and rebinding
文献类型：期刊论文
| 作者 | Chen, Zhiyong; Hua, Zhendong; Xu, Li; Huang, Yong; Zhao, Meiping; Li, Yuanzong |
| 刊名 | journal of molecular recognition
 |
| 出版日期 | 2008 |
| 卷号 | 21期号:1页码:71-77 |
| 关键词 | molecularly imprinted polymer (MIP) hydrogel specific shrinking protein recognition |
| 英文摘要 | stimuli-responsive protein imprinted polymers were obtained via a combination of molecular imprinting and reversible stimuli-responsive polymer using lysozyme or cytochrome c as template, n-isopropylacrylamide (nipa) as major monomer, methacrylic acid (maa) and acrylamide (aam) as functional co-monomers, and n,n-methylenebisacrylamide (mbaam) as crosslinker. the molecularly imprinted polymers (mips) can respond not only to external stimuli such as temperature and salt concentration, but also to the corresponding template protein with significant specific volume shrinking. this specific shrinking behavior was attributed to the synergistic effect of multiple-site weak interactions (electrostatic force, hydrogen bonding and hydrophobic interaction) and the cavity effect. the mips showed highly selective adsorption of template proteins with specific shrinking compared with the non-imprinted polymers. the results indicated that the mips seemed to change shape to accommodate the conformation of the template protein leading to the formation of a shape complementary cavity. copyright (c) 2008 john wiley & sons, ltd. |
| WOS标题词 | science & technology ; life sciences & biomedicine |
| 类目[WOS] | biochemistry & molecular biology ; biophysics |
| 研究领域[WOS] | biochemistry & molecular biology ; biophysics |
| 关键词[WOS] | artificial antibodies ; hydrogels ; recognition ; gels ; lysozyme ; molecules ; release ; beads |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000253689800008 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/141226]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Peking Univ, Coll Chem & Mol Engn, Key Lab Bioorgan Chem & Mol Engn, BNLMS, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Zhiyong,Hua, Zhendong,Xu, Li,et al. Protein-responsive imprinted polymers with specific shrinking and rebinding[J]. journal of molecular recognition,2008,21(1):71-77. |
| APA | Chen, Zhiyong,Hua, Zhendong,Xu, Li,Huang, Yong,Zhao, Meiping,&Li, Yuanzong.(2008).Protein-responsive imprinted polymers with specific shrinking and rebinding.journal of molecular recognition,21(1),71-77. |
| MLA | Chen, Zhiyong,et al."Protein-responsive imprinted polymers with specific shrinking and rebinding".journal of molecular recognition 21.1(2008):71-77. |
入库方式： OAI收割
来源：大连化学物理研究所
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