Systematic screening and characterization of tertiary and quaternary alkaloids from corydalis yanhusuo W.T. Wang using ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry
文献类型：期刊论文
| 作者 | Zhang, Jing1; Jin, Yu2; Dong, Jun1; Xiao, Yuansheng1; Feng, Jiatao1; Xue, Xingya1; Zhang, Xiuli1; Liang, Xinmiao1 |
| 刊名 | talanta
 |
| 出版日期 | 2009-04-30 |
| 卷号 | 78期号:2页码:513-522 |
| 关键词 | UPLC/Q-TOF MS/MS Screening Alkaloids Corydalis yanhusuo WT Wang |
| 英文摘要 | ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (uplc-q-tof-ms) is an effective technique for analysis of complex samples with offering rapid efficient separation. in combination with accurate mass measurement and tandem mass spectrometry (ms/ms) this a er exploits this technique to identify the alkaloids in corydalis yanhusuo, an important antalgic traditional chinese medicine (tcm). the mass spectral fragmentation behavior of one tertiary alkaloid and two quaternary alkaloids was studied in detail. low-abundance product ions of tertiary and quaternary alkaloids were investigated and compared between each other. sixteen alkaloids were screened out by using a systematic screening method developed in our laboratory; structures of eight therein were identified by characteristic uv absorption spectrum and positive ion mode of q-tof-ms/ms; and two of them were discovered for the first time in corydalis yanhusuo to our knowledge. this research demonstrates the potential of uplc-q-tof-ms in structural characterization and identification of components in traditional chinese herbal medicines. (c) 2008 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | tetrahydropalmatine ; protoberberine ; identification ; separation ; extract ; ms |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000264043400028 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/141475]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 2.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Jing,Jin, Yu,Dong, Jun,et al. Systematic screening and characterization of tertiary and quaternary alkaloids from corydalis yanhusuo W.T. Wang using ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry[J]. talanta,2009,78(2):513-522. |
| APA | Zhang, Jing.,Jin, Yu.,Dong, Jun.,Xiao, Yuansheng.,Feng, Jiatao.,...&Liang, Xinmiao.(2009).Systematic screening and characterization of tertiary and quaternary alkaloids from corydalis yanhusuo W.T. Wang using ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry.talanta,78(2),513-522. |
| MLA | Zhang, Jing,et al."Systematic screening and characterization of tertiary and quaternary alkaloids from corydalis yanhusuo W.T. Wang using ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry".talanta 78.2(2009):513-522. |
入库方式： OAI收割
来源：大连化学物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。