Evaluation of the interaction of bioactive compounds in Cortex Pseudolarix and Radix Stephaniae by the microdialysis probe coupled with high performance liquid chromatography-mass spectrometry
文献类型：期刊论文
| 作者 | Lei, Xiaoyuan2; Kong, Liang1,2; Zou, Hanfa2; Ma, Hong2; Yang, Ling2 |
| 刊名 | journal of chromatography a
 |
| 出版日期 | 2009-03-13 |
| 卷号 | 1216期号:11页码:2179-2184 |
| 关键词 | Biological fingerprinting chromatogram analysis Cortex Pseudolarix Radix Stephaniae MCF-7 Multidrug resistance |
| 英文摘要 | an efficient and convenient method, biological fingerprinting chromatogram analysis is presented. which is applied to the comparison or finger printing chromatograms of the extracts of chinese herbal medicines after the interaction with biological systems (cell, dna, protein, etc.). the method was established for the purpose of screening and analysis of the multiple bioactive compounds in herbal medicines. in this work, microdialysis sampling combined with high performance liquid chromatography-mass spectrometry (hplc-ms) was studied for binding property of mcf 7 and multidrug resistant mcf-7 cell systems. the results showed that pseudolaric acid a (paa) and pseudolaric acid b (pab) in the cortex of pseudolarix kaempferi (lamb.) gorden can easily bind to the mcf-7 cells ranging from 0 to 16.3% (paa) and from 0 to 35.7% (pab), and another compound, tetrandrine (tet) from the root of stephania tetrandrae s. moore, showed higher binding activity with multidrug resistant mcf-7 cells ranging from 0 to 39.9%. (c) 2008 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | traditional chinese medicines ; gene-expression patterns ; multidrug-resistance ; dna ; microarray ; products ; binding ; protein ; cells ; hplc |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000264226500027 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/141566]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Dalian Fisheries Univ, Coll Marine Environm Engn, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lei, Xiaoyuan,Kong, Liang,Zou, Hanfa,et al. Evaluation of the interaction of bioactive compounds in Cortex Pseudolarix and Radix Stephaniae by the microdialysis probe coupled with high performance liquid chromatography-mass spectrometry[J]. journal of chromatography a,2009,1216(11):2179-2184. |
| APA | Lei, Xiaoyuan,Kong, Liang,Zou, Hanfa,Ma, Hong,&Yang, Ling.(2009).Evaluation of the interaction of bioactive compounds in Cortex Pseudolarix and Radix Stephaniae by the microdialysis probe coupled with high performance liquid chromatography-mass spectrometry.journal of chromatography a,1216(11),2179-2184. |
| MLA | Lei, Xiaoyuan,et al."Evaluation of the interaction of bioactive compounds in Cortex Pseudolarix and Radix Stephaniae by the microdialysis probe coupled with high performance liquid chromatography-mass spectrometry".journal of chromatography a 1216.11(2009):2179-2184. |
入库方式： OAI收割
来源：大连化学物理研究所
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