中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Synthesis and application of photoaffinity probe containing an intact isoprenoid chain

文献类型:期刊论文

作者Li, Lingdong1,2; Tang, Wei1,2; Zhao, Zongbao Kent1
刊名bioorganic & medicinal chemistry letters
出版日期2009-08-15
卷号19期号:16页码:4824-4826
关键词Isoprenoid chain Chemical probe Photoaffinity labeling Streptavidin blot
英文摘要two novel chemical probes each carrying an intact isoprenoid chain, a biotin tag and a benzophenone moiety were synthesized. photoaffinity labeling of the saccharomyces cerevisiae cell lysate revealed that these probes could selectively trap some proteins, and proteins with molecular weight of similar to 70 kda appeared as a major band upon streptavidin blot analysis. (c) 2009 elsevier ltd. all rights reserved.
WOS标题词science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]chemistry, medicinal ; chemistry, organic
研究领域[WOS]pharmacology & pharmacy ; chemistry
关键词[WOS]farnesyl transferase ; diphosphate analogs ; protein ; prenyltransferases ; esters ; biochemistry ; inhibitors ; alcohols
收录类别SCI
语种英语
WOS记录号WOS:000268358800065
公开日期2015-11-17
源URL[http://159.226.238.44/handle/321008/141588]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
作者单位1.CAS, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Li, Lingdong,Tang, Wei,Zhao, Zongbao Kent. Synthesis and application of photoaffinity probe containing an intact isoprenoid chain[J]. bioorganic & medicinal chemistry letters,2009,19(16):4824-4826.
APA Li, Lingdong,Tang, Wei,&Zhao, Zongbao Kent.(2009).Synthesis and application of photoaffinity probe containing an intact isoprenoid chain.bioorganic & medicinal chemistry letters,19(16),4824-4826.
MLA Li, Lingdong,et al."Synthesis and application of photoaffinity probe containing an intact isoprenoid chain".bioorganic & medicinal chemistry letters 19.16(2009):4824-4826.

入库方式: OAI收割

来源:大连化学物理研究所

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