Synthesis and application of photoaffinity probe containing an intact isoprenoid chain
文献类型:期刊论文
作者 | Li, Lingdong1,2; Tang, Wei1,2; Zhao, Zongbao Kent1 |
刊名 | bioorganic & medicinal chemistry letters |
出版日期 | 2009-08-15 |
卷号 | 19期号:16页码:4824-4826 |
关键词 | Isoprenoid chain Chemical probe Photoaffinity labeling Streptavidin blot |
英文摘要 | two novel chemical probes each carrying an intact isoprenoid chain, a biotin tag and a benzophenone moiety were synthesized. photoaffinity labeling of the saccharomyces cerevisiae cell lysate revealed that these probes could selectively trap some proteins, and proteins with molecular weight of similar to 70 kda appeared as a major band upon streptavidin blot analysis. (c) 2009 elsevier ltd. all rights reserved. |
WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
类目[WOS] | chemistry, medicinal ; chemistry, organic |
研究领域[WOS] | pharmacology & pharmacy ; chemistry |
关键词[WOS] | farnesyl transferase ; diphosphate analogs ; protein ; prenyltransferases ; esters ; biochemistry ; inhibitors ; alcohols |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000268358800065 |
公开日期 | 2015-11-17 |
源URL | [http://159.226.238.44/handle/321008/141588] |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | 1.CAS, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Lingdong,Tang, Wei,Zhao, Zongbao Kent. Synthesis and application of photoaffinity probe containing an intact isoprenoid chain[J]. bioorganic & medicinal chemistry letters,2009,19(16):4824-4826. |
APA | Li, Lingdong,Tang, Wei,&Zhao, Zongbao Kent.(2009).Synthesis and application of photoaffinity probe containing an intact isoprenoid chain.bioorganic & medicinal chemistry letters,19(16),4824-4826. |
MLA | Li, Lingdong,et al."Synthesis and application of photoaffinity probe containing an intact isoprenoid chain".bioorganic & medicinal chemistry letters 19.16(2009):4824-4826. |
入库方式: OAI收割
来源:大连化学物理研究所
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