Homogeneous synthesis of GRGDY grafted chitosan on hydroxyl groups by photochemical reaction for improved cell adhesion
文献类型：期刊论文
| 作者 | Yang, Yan2,3; Liu, Xiudong1; Yu, Weiting2; Zhou, Houjiang2,3; Li, Xiaoxia2,3; Ma, Xiaojun2 |
| 刊名 | carbohydrate polymers
 |
| 出版日期 | 2010-05-05 |
| 卷号 | 80期号:3页码:733-739 |
| 关键词 | Homogeneous synthesis Chitosan Hydroxyl Photochemistry Cell adhesion |
| 英文摘要 | a novel homogeneous synthesis route was presented to produce rgd-containing peptide modified chitosan (cts) with purpose of improving cell adhesion and growth. bifunctional photosensitive crosslinker, sulfo-sanpah, was used to link cell adhesive peptide grgdy and cts under controlled condition. the synthesis process was proved by ftir, maldi-tof ms and (1)h nmr analyses, and the mechanism was demonstrated clearly and completely that hydroxyl groups of cts were prior: to amino groups for nucleophilic reaction with sulfo-sanpah. moreover, cell adhesion and proliferation were evaluated for grgdy grafted cts. the results showed that grgdy grafted cts formed by the novel strategy had potential application not only as drug or gene carriers but also as tissue engineered scaffolds. (c) 2009 elsevier ltd. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, applied ; chemistry, organic ; polymer science |
| 研究领域[WOS] | chemistry ; polymer science |
| 关键词[WOS] | arg-gly-asp ; human endothelial-cells ; in-vivo ; chitosan-graft-poly(ethylene glycol) ; drug-delivery ; rgd peptide ; growth ; surface ; proliferation ; nanoparticle |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000276987800015 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/141786]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Dalian Univ, Coll Environm & Chem Engn, Dalian 116622, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Biomed Mat Engn, Dalian 116023, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Yan,Liu, Xiudong,Yu, Weiting,et al. Homogeneous synthesis of GRGDY grafted chitosan on hydroxyl groups by photochemical reaction for improved cell adhesion[J]. carbohydrate polymers,2010,80(3):733-739. |
| APA | Yang, Yan,Liu, Xiudong,Yu, Weiting,Zhou, Houjiang,Li, Xiaoxia,&Ma, Xiaojun.(2010).Homogeneous synthesis of GRGDY grafted chitosan on hydroxyl groups by photochemical reaction for improved cell adhesion.carbohydrate polymers,80(3),733-739. |
| MLA | Yang, Yan,et al."Homogeneous synthesis of GRGDY grafted chitosan on hydroxyl groups by photochemical reaction for improved cell adhesion".carbohydrate polymers 80.3(2010):733-739. |
入库方式： OAI收割
来源：大连化学物理研究所
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