CYP3A catalyses schizandrin biotransformation in human, minipig and rat liver microsomes
文献类型：期刊论文
| 作者 | Cao, Y. -F.1; Zhang, Y. -Y.2,3; Li, J.1; Ge, G. -B.2; Hu, D.1; Liu, H. -X.2,3; Huang, T.1; Wang, Y. -C.1; Fang, Z. -Z.2,3; Sun, D. -X.1 |
| 刊名 | xenobiotica
 |
| 出版日期 | 2010 |
| 卷号 | 40期号:1页码:38-47 |
| 关键词 | Schizandrin cytochrome P450 microsomes metabolism Fructus schisandrae |
| 英文摘要 | 1. schizandrin is recognized as the major absorbed effective constituent of fructus schisandrae, which is extensively applied in chinese medicinal formula. the present study aimed to profile the phase i metabolites of schizandrin and identify the cytochrome p450 (cyp) isoforms involved. |
| WOS标题词 | science & technology ; life sciences & biomedicine |
| 类目[WOS] | pharmacology & pharmacy ; toxicology |
| 研究领域[WOS] | pharmacology & pharmacy ; toxicology |
| 关键词[WOS] | human cytochrome-p450 enzymes ; medroxyprogesterone acetate ; in-vitro ; metabolism ; inhibition ; extract ; fruit ; isoforms ; plasma ; vivo |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000272796100004 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/141814]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Shenyang Pharmaceut Univ, Sch Tradit Chinese Med, Shenyang 110016, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cao, Y. -F.,Zhang, Y. -Y.,Li, J.,et al. CYP3A catalyses schizandrin biotransformation in human, minipig and rat liver microsomes[J]. xenobiotica,2010,40(1):38-47. |
| APA | Cao, Y. -F..,Zhang, Y. -Y..,Li, J..,Ge, G. -B..,Hu, D..,...&Yang, L..(2010).CYP3A catalyses schizandrin biotransformation in human, minipig and rat liver microsomes.xenobiotica,40(1),38-47. |
| MLA | Cao, Y. -F.,et al."CYP3A catalyses schizandrin biotransformation in human, minipig and rat liver microsomes".xenobiotica 40.1(2010):38-47. |
入库方式： OAI收割
来源：大连化学物理研究所
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