中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Effects of exogenous methyl jasmonate on artemisinin biosynthesis and secondary metabolites in Artemisia annua L.

文献类型:期刊论文

作者Wang, Huahong1,4; Ma, Chenfei2; Li, Zhenqiu3; Ma, Lanqing1; Wang, Hong1; Ye, Hechun1; Xu, Guowang2; Liu, Benye1
刊名industrial crops and products
出版日期2010-03-01
卷号31期号:2页码:214-218
关键词Artemisia annua L. GC-MS Artemisinin Metabolite profiling Methyl jasmonate
英文摘要artemisin is a sesquiterpene lactone with an endoperoxide bridge first isolated from the aerial parts of artemisia annua l (compositae). it is an important antimalarial component, but as of present remains quite expensive due to its low content in the plant, the only commercial source of the compound. in this study, we found a 49% increase of the artemisinin content in a. annua sp18 on day 8 after treatment with methyl jasmonate (meja), together with an 80% increase in artemisinic acid and 28% in dihydroartemisinic acid, the two potential precursors of artemisinin. in addition, the effects of exogenous meja on other secondary metabolites were evaluated by metabolite profiling using orthogonal signal correction partial least square discriminant analysis (osc-pls). six sesquiterpenoids and three triterpenoids were selected as marker compounds in osc-pls. their content also changed significantly after meja treatment, including a 50% increase in methyl artemisinic acid, a 67% increase in squalene and a 60% increase in peak 51 (an unidentified sesquiterpenoid). these compounds are promising targets for further studies on artemisinin biosynthesis and metabolic engineering. (c) 2009 elsevier b.v. all rights reserved.
WOS标题词science & technology ; life sciences & biomedicine
类目[WOS]agricultural engineering ; agronomy
研究领域[WOS]agriculture
关键词[WOS]volatile terpene biosynthesis ; antimalarial-drug ; glandular trichomes ; induction ; acid ; cultures ; foliage ; plants
收录类别SCI
语种英语
WOS记录号WOS:000275972700003
公开日期2015-11-17
源URL[http://159.226.238.44/handle/321008/141992]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Key Lab Photosynth & Environm Mol Physiol, Inst Bot, Beijing 100093, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China
3.Hebei Univ, Coll Life Sci, Baoding 071002, Peoples R China
4.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714
Wang, Huahong,Ma, Chenfei,Li, Zhenqiu,et al. Effects of exogenous methyl jasmonate on artemisinin biosynthesis and secondary metabolites in Artemisia annua L.[J]. industrial crops and products,2010,31(2):214-218.
APA Wang, Huahong.,Ma, Chenfei.,Li, Zhenqiu.,Ma, Lanqing.,Wang, Hong.,...&Liu, Benye.(2010).Effects of exogenous methyl jasmonate on artemisinin biosynthesis and secondary metabolites in Artemisia annua L..industrial crops and products,31(2),214-218.
MLA Wang, Huahong,et al."Effects of exogenous methyl jasmonate on artemisinin biosynthesis and secondary metabolites in Artemisia annua L.".industrial crops and products 31.2(2010):214-218.

入库方式: OAI收割

来源:大连化学物理研究所

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