中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis

文献类型:期刊论文

作者Yu, Fengjiao1; Kong, Liang1,2; Zou, Hanfa2; Lei, Xiaoyuan2
刊名combinatorial chemistry & high throughput screening
出版日期2010-12-01
卷号13期号:10页码:855-868
关键词Traditional Chinese medicines (TCMs) biological fingerprinting analysis screening bioactive components/compounds omics
英文摘要traditional chinese medicines (tcms), a key branch of natural medicines, play an important role in the treatment of diseases because of their reliable clinical performance. identification of their active compounds constitutes a bottleneck in the development of tcms. screening and analysis of active compounds is a challenge in tcm research. this review summarizes recent progress in the development of biological fingerprinting strategies for screening and analyzing bioactive compounds in tcms using molecular recognition, metabolism and omics tools. the evaluated strategies include the following techniques: microdialysis/centrifugal ultrafiltration-hplc, biochromatography, metabolic fingerprinting analysis, 2-dimensional biochromatography and omics fingerprinting analysis.
WOS标题词science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]biochemical research methods ; chemistry, applied ; pharmacology & pharmacy
研究领域[WOS]biochemistry & molecular biology ; chemistry ; pharmacology & pharmacy
关键词[WOS]immobilized liposome chromatography ; performance liquid-chromatography ; human serum-albumin ; ionization mass-spectrometer ; longdan-xiegan-decoction ; drug discovery ; affinity-chromatography ; stationary-phase ; active compounds ; molecular biochromatography
收录类别SCI
语种英语
WOS记录号WOS:000284622300005
公开日期2015-11-17
源URL[http://159.226.238.44/handle/321008/142168]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
作者单位1.Dalian Ocean Univ, Key Lab Offshore Marine Environm Res Liaoning Hig, Dalian 116023, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714
Yu, Fengjiao,Kong, Liang,Zou, Hanfa,et al. Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis[J]. combinatorial chemistry & high throughput screening,2010,13(10):855-868.
APA Yu, Fengjiao,Kong, Liang,Zou, Hanfa,&Lei, Xiaoyuan.(2010).Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis.combinatorial chemistry & high throughput screening,13(10),855-868.
MLA Yu, Fengjiao,et al."Progress on the Screening and Analysis of Bioactive Compounds in Traditional Chinese Medicines by Biological Fingerprinting Analysis".combinatorial chemistry & high throughput screening 13.10(2010):855-868.

入库方式: OAI收割

来源:大连化学物理研究所

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