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Characterization of steroidal saponins in crude extracts from Dioscorea zingiberensis C. H. Wright by ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry

文献类型:期刊论文

作者Zhu, Jingbo1; Guo, Xiujie1; Fu, Shaoping1; Zhang, Xiuli2; Liang, Xinmiao2
刊名journal of pharmaceutical and biomedical analysis
出版日期2010-11-02
卷号53期号:3页码:462-474
关键词Steroidal saponin Dioscorea zingiberensis C H Wright UPLC Q-TOF-MS/MS Structural elucidation
英文摘要steroidal saponins are the major bioactive constituents of dioscorea zingiberensis c h wright (d zingiberensis) in this work, ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry (uplc/q-tof-ms/ms) was applied to the separation and characterization of steroidal saponins in crude extracts from d zingiberensis. the results showed that fragment ions from glycosidic and cross-ring cleavages gave a wealth of structural information related to aglycone skeletons, sugar types and the sequence of sugar units. according to the summarized fragmentation patterns, identification of steroidal saponins from d zingiberensis could be fulfilled, even when reference standards were unavailable as a result, a total of thirty-one saponins with five aglycone skeletons, including fourteen new trace saponins, were identified or tentatively elucidated in crude extracts from d zingiberensis based on their retention times, the mass spectrometric fragmentation patterns, and ms and ms/ms data (c) 2010 elsevier b v all rights reserved
WOS标题词science & technology ; physical sciences ; life sciences & biomedicine
类目[WOS]chemistry, analytical ; pharmacology & pharmacy
研究领域[WOS]chemistry ; pharmacology & pharmacy
关键词[WOS]electrospray-ionization ; structural-characterization ; antineoplastic agents ; rapid identification ; rhizomes ; glycosides ; hypoglauca ; ms/ms
收录类别SCI
语种英语
WOS记录号WOS:000280435800033
公开日期2015-11-17
源URL[http://159.226.238.44/handle/321008/142222]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
作者单位1.Dalian Polytech Univ, Inst Chem & Applicat Plant Resource, Sch Biol & Food Engn, Dalian 116034, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
推荐引用方式
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Zhu, Jingbo,Guo, Xiujie,Fu, Shaoping,et al. Characterization of steroidal saponins in crude extracts from Dioscorea zingiberensis C. H. Wright by ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry[J]. journal of pharmaceutical and biomedical analysis,2010,53(3):462-474.
APA Zhu, Jingbo,Guo, Xiujie,Fu, Shaoping,Zhang, Xiuli,&Liang, Xinmiao.(2010).Characterization of steroidal saponins in crude extracts from Dioscorea zingiberensis C. H. Wright by ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry.journal of pharmaceutical and biomedical analysis,53(3),462-474.
MLA Zhu, Jingbo,et al."Characterization of steroidal saponins in crude extracts from Dioscorea zingiberensis C. H. Wright by ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry".journal of pharmaceutical and biomedical analysis 53.3(2010):462-474.

入库方式: OAI收割

来源:大连化学物理研究所

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