Preparation of Perphenylcarbamoylated beta-Cyclodextrin-silica Hybrid Monolithic Column with "One-Pot" Approach for Enantioseparation by Capillary Liquid Chromatography
文献类型：期刊论文
| 作者 | Zhang, Zhenbin1,2; Wu, Minghuo1; Wu, Ren'an1; Done, Jing1; Ou, Junjie1; Zou, Hanfa1 |
| 刊名 | analytical chemistry
 |
| 出版日期 | 2011-05-01 |
| 卷号 | 83期号:9页码:3616-3622 |
| 英文摘要 | perphenylcarbamoylated beta-cycloclextrin-silica (ph-beta-cd-silica) hybrid monolithic columns for enantioseparation in capillary liquid chromatography (clc) have been prepared by a "one-pot" approach via the polycondensation of alkoxysilanes and in situ copolymerization of mono (6(a)-n-allylamino-6(a)-deoxy)-ph-beta-cd and vinyl group on the precondensed siloxanes. the morphologies of the ph-beta-cd-silica hybrid monolithic columns were characterized by optical microscopy and scanning electron microscopy (sem), showing the uniform monolithic matrixes tightly bonded onto the capillary wall. the content of ph-beta-cd incorporated in monolithic matrix by the "one-pot" approach was ca. 2.9 times higher than that by postmodification method. the permeability of the ph-beta-cd-silica chiral hybrid monolithic column was 3.63 x 10(-14) m(2), and the minimum plate height was 12 pm corresponding to 83 300 theoretical plates/meter. enantioseparations of 13 racemates were achieved by the ph-beta-cd-silica hybrid monolithic column. in this work, since the prepolymerization system mainly consisted of organic solvent (methanol (meoh), n, n-dimethylformamide (dmf)), the limitation and difficulty of the use of water insoluble organic monomers in the previously reported "one-pot" method was circumvented. therefore, various beta-cd derivatives as well as other hydrophobic monomers could thus be used to prepare organic silica hybrid monolithic columns with the "one-pot" process. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | chiral stationary-phase ; charged polyacrylamide-gels ; enantiomeric separations ; bonded silica ; neutral compounds ; electrochromatography ; hplc ; cec ; polymerization ; derivatives |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000289956800058 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/142538]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Zhenbin,Wu, Minghuo,Wu, Ren'an,et al. Preparation of Perphenylcarbamoylated beta-Cyclodextrin-silica Hybrid Monolithic Column with "One-Pot" Approach for Enantioseparation by Capillary Liquid Chromatography[J]. analytical chemistry,2011,83(9):3616-3622. |
| APA | Zhang, Zhenbin,Wu, Minghuo,Wu, Ren'an,Done, Jing,Ou, Junjie,&Zou, Hanfa.(2011).Preparation of Perphenylcarbamoylated beta-Cyclodextrin-silica Hybrid Monolithic Column with "One-Pot" Approach for Enantioseparation by Capillary Liquid Chromatography.analytical chemistry,83(9),3616-3622. |
| MLA | Zhang, Zhenbin,et al."Preparation of Perphenylcarbamoylated beta-Cyclodextrin-silica Hybrid Monolithic Column with "One-Pot" Approach for Enantioseparation by Capillary Liquid Chromatography".analytical chemistry 83.9(2011):3616-3622. |
入库方式： OAI收割
来源：大连化学物理研究所
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