Selective Enrichment of Endogenous Serum Phosphopeptides with Ultrafiltration Membrane Intercept-Titanium Dioxide Chromatography Coupled with Nano Ultra High Pressure Liquid Chromatography-Quadrupole-Time of Flight Mass Spectrometry
文献类型：期刊论文
| 作者 | Zou Li-Juan2; Li Juan2; Wan Hui-Hui1; Li Xiu-Ling1; Liang Xin-Miao1 |
| 刊名 | chinese journal of analytical chemistry
 |
| 出版日期 | 2011-12-01 |
| 卷号 | 39期号:12页码:1781-1786 |
| 关键词 | Ultrafiltration Membrane Titanium dioxide Enrichment Endogenous serum phosphopeptides Nano ultra high pressure liquid chromatography-quadrupole-time of flight mass spectrometry |
| 英文摘要 | a novel method coupled ultrafiltration membrane with tio2 was developed to remove large amount high-molecular weight compounds and enrich endogenous phosphopeptides in serum. the enriched endogenous serum phosphopeptides were characterized by nano ultra-high pressure liquid chromatography-quadrupole-time of flight ms ( nano uplc-q-tof ms). up to 18 endogenous phosphopeptides could be successfully identified from the serum of lung cancer. the sensitivity and efficiency of serum phosphopeptides detection was improved by this established method, which might be contributed to novel tumor biomarker discovery. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | phosphorylated peptides ; phosphoproteome ; tools |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000300598000001 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/142580]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Dalian Med Univ, Affiliated Hosp 2, Dalian 116044, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zou Li-Juan,Li Juan,Wan Hui-Hui,et al. Selective Enrichment of Endogenous Serum Phosphopeptides with Ultrafiltration Membrane Intercept-Titanium Dioxide Chromatography Coupled with Nano Ultra High Pressure Liquid Chromatography-Quadrupole-Time of Flight Mass Spectrometry[J]. chinese journal of analytical chemistry,2011,39(12):1781-1786. |
| APA | Zou Li-Juan,Li Juan,Wan Hui-Hui,Li Xiu-Ling,&Liang Xin-Miao.(2011).Selective Enrichment of Endogenous Serum Phosphopeptides with Ultrafiltration Membrane Intercept-Titanium Dioxide Chromatography Coupled with Nano Ultra High Pressure Liquid Chromatography-Quadrupole-Time of Flight Mass Spectrometry.chinese journal of analytical chemistry,39(12),1781-1786. |
| MLA | Zou Li-Juan,et al."Selective Enrichment of Endogenous Serum Phosphopeptides with Ultrafiltration Membrane Intercept-Titanium Dioxide Chromatography Coupled with Nano Ultra High Pressure Liquid Chromatography-Quadrupole-Time of Flight Mass Spectrometry".chinese journal of analytical chemistry 39.12(2011):1781-1786. |
入库方式： OAI收割
来源：大连化学物理研究所
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