Separation of enantiomers of drugs by capillary electrophoresis .4. Hydroxypropyl-gamma-cyclodextrin as chiral solvating agent
文献类型：期刊论文
| 作者 | Koppenhoefer, B; Epperlein, U; Zhu, XF; Lin, BC |
| 刊名 | electrophoresis
 |
| 出版日期 | 1997-06-01 |
| 卷号 | 18期号:6页码:924-930 |
| 关键词 | capillary electrophoresis enantiomer separation chiral drugs hydroxypropyl-gamma-cyclodextrin |
| 英文摘要 | in an extended chiral drug screening program, enantioseparation of 86 racemic drugs was tested with hydroxypropyl-gamma-cyclodextrin as chiral solvating agent (csa). a total of 30 drugs out of 86 could be resolved in this straightforward approach. the number of experiments performed under identical conditions allows a statistical treatment of the data. the enantioseparation of the analytes is correlated with their interaction strength with the csa. hence, the concentration of the csa is a crucial parameter for optimization of the enantioseparation, as shown by a subset of 23 examples. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | beta-cyclodextrin ; electrokinetic chromatography ; zone electrophoresis ; resolution ; micelles ; model |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:A1997XH29300011 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/142804]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | INST CHEM PHYS,DALIAN,PEOPLES R CHINA |
| 推荐引用方式 GB/T 7714 | Koppenhoefer, B,Epperlein, U,Zhu, XF,et al. Separation of enantiomers of drugs by capillary electrophoresis .4. Hydroxypropyl-gamma-cyclodextrin as chiral solvating agent[J]. electrophoresis,1997,18(6):924-930. |
| APA | Koppenhoefer, B,Epperlein, U,Zhu, XF,&Lin, BC.(1997).Separation of enantiomers of drugs by capillary electrophoresis .4. Hydroxypropyl-gamma-cyclodextrin as chiral solvating agent.electrophoresis,18(6),924-930. |
| MLA | Koppenhoefer, B,et al."Separation of enantiomers of drugs by capillary electrophoresis .4. Hydroxypropyl-gamma-cyclodextrin as chiral solvating agent".electrophoresis 18.6(1997):924-930. |
入库方式： OAI收割
来源：大连化学物理研究所
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