Asymmetric Organocatalytic Cascade Michael/Michael/Henry Reaction Sequence: Control of All Stereocenters in One Cyclohexane Skeleton
文献类型：期刊论文
| 作者 | Mao, Zhifeng1,2,3; Jia, Yaomei1,2; Xu, Zhaoqing3; Wang, Rui1,2 |
| 刊名 | advanced synthesis & catalysis
 |
| 出版日期 | 2012-05-01 |
| 卷号 | 354期号:8页码:1401-1406 |
| 关键词 | asymmetric catalysis cyclohexanes domino reactions Henry reaction Michael addition |
| 英文摘要 | the highly diastereo- and enantioselective relay cascade michael/michael/henry reaction catalyzed by combination of readily available diphenylprolinol silyl ether and the quinine thiourea in a one-pot fashion has been developed. up to 70% yield and up to >99% enantioselectivity of the single major isomer were obtained from the cascade reactions. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, applied ; chemistry, organic |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | diphenylprolinol silyl ether ; michael-henry reactions ; high-yielding synthesis ; functionalized cyclohexanes ; inhibitor (-)-oseltamivir ; contiguous stereocenters ; bifunctional thiourea ; tandem reactions ; bond donors ; catalysis |
| 收录类别 | SCI ; IC ; CCR |
| 语种 | 英语 |
| WOS记录号 | WOS:000304345100003 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/142942]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Lanzhou Univ, Sch Basic Med Sci, Key Lab Preclin Study New Drugs Gansu Prov, Inst Biochem & Mol Biol,Sch Life Sci, Lanzhou 730000, Peoples R China 2.Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Mao, Zhifeng,Jia, Yaomei,Xu, Zhaoqing,et al. Asymmetric Organocatalytic Cascade Michael/Michael/Henry Reaction Sequence: Control of All Stereocenters in One Cyclohexane Skeleton[J]. advanced synthesis & catalysis,2012,354(8):1401-1406. |
| APA | Mao, Zhifeng,Jia, Yaomei,Xu, Zhaoqing,&Wang, Rui.(2012).Asymmetric Organocatalytic Cascade Michael/Michael/Henry Reaction Sequence: Control of All Stereocenters in One Cyclohexane Skeleton.advanced synthesis & catalysis,354(8),1401-1406. |
| MLA | Mao, Zhifeng,et al."Asymmetric Organocatalytic Cascade Michael/Michael/Henry Reaction Sequence: Control of All Stereocenters in One Cyclohexane Skeleton".advanced synthesis & catalysis 354.8(2012):1401-1406. |
入库方式： OAI收割
来源：大连化学物理研究所
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