A new electronically deficient atropisomeric diphosphine ligand (S)-CF3O-BiPhep and its application in asymmetric hydrogenation
文献类型：期刊论文
| 作者 | Zhang, De-Yang1,2; Yu, Chang-Bin2; Wang, Min-Can1; Gao, Kai2; Zhou, Yong-Gui2 |
| 刊名 | tetrahedron letters
 |
| 出版日期 | 2012-05-16 |
| 卷号 | 53期号:20页码:2556-2559 |
| 关键词 | Asymmetric catalysis Fluorinated diphosphine ligands Quinolines Indoles |
| 英文摘要 | a new electronically deficient atropisomeric diphosphine ligand (s)-cf3o-biphep was synthesized from 1-bromo-3-(trifluoromethoxy)benzene in high yield. the key steps included oxidative coupling with anhydrous ferric chloride and optical resolution by (+)-dmta. the ligand afforded high performance for ir-catalyzed asymmetric hydrogenation of quinolines with ee up to 92% and ton up to 25,000. it was also successfully applied to the pd-catalyzed asymmetric hydrogenation of simple indoles with ee up to 87% and rh-catalyzed asymmetric 1,4-addition of phenylboronic acid to 2-cyclohexenone with 97% ee. (c) 2012 elsevier ltd. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, organic |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | highly enantioselective hydrogenation ; iridium-catalyzed hydrogenation ; heteroaromatic-compounds ; arylboronic acids ; bisphosphine ligands ; diene ligands ; quinolines ; 1,4-addition ; indoles ; difluorphos |
| 收录类别 | SCI ; IC ; CCR |
| 语种 | 英语 |
| WOS记录号 | WOS:000303372200018 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/142978]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Zhengzhou Univ, Dept Chem, Zhengzhou 450052, Henan, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Catalysis, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, De-Yang,Yu, Chang-Bin,Wang, Min-Can,et al. A new electronically deficient atropisomeric diphosphine ligand (S)-CF3O-BiPhep and its application in asymmetric hydrogenation[J]. tetrahedron letters,2012,53(20):2556-2559. |
| APA | Zhang, De-Yang,Yu, Chang-Bin,Wang, Min-Can,Gao, Kai,&Zhou, Yong-Gui.(2012).A new electronically deficient atropisomeric diphosphine ligand (S)-CF3O-BiPhep and its application in asymmetric hydrogenation.tetrahedron letters,53(20),2556-2559. |
| MLA | Zhang, De-Yang,et al."A new electronically deficient atropisomeric diphosphine ligand (S)-CF3O-BiPhep and its application in asymmetric hydrogenation".tetrahedron letters 53.20(2012):2556-2559. |
入库方式： OAI收割
来源：大连化学物理研究所
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