Amino Acid Ionic Liquid Modified Mesoporous Carbon: A Tailor-made Nanostructure Biosensing Platform
文献类型：期刊论文
| 作者 | Wu, Lidong; Lu, Xianbo; Zhang, Haijun; Chen, Jiping |
| 刊名 | chemsuschem
 |
| 出版日期 | 2012 |
| 卷号 | 5期号:10页码:1918-1925 |
| 关键词 | biosensors carbon materials enzymes room temperature ionic liquids (RTILs) phenol |
| 英文摘要 | a novel nanocomposite based on ordered graphitized mesoporous carbon (gmc) and amino acid ionic liquids (aail) is obtained through controlled surface modification of gmc with hydrophilic aails (1-ethyl-3-methylimidazolium alanine, emim[ala]), which is used as a platform for a tyrosinase biosensor to detect phenol. the gmcaail nanocomposite possesses a better biocompatibility and improved aqueous-phase dispersion than hydrophobic gmc alone, owing to the introduction of hydrophilic and biocompatible aails. comparative studies revealed that the catalytic activity of tyrosinase for phenol in phosphate buffer solution (pbs) containing emim[ala] was about ten times higher than that in pure pbs. by entrapping tyrosinase molecules into the mesopores of gmc, making use of the synergy effect of gmc and aail (the interspace confinement effect, the anti-fouling ability, and the biocompatible microenvironment), the gmcaail-based biosensors display superior analytical performance to gmc-based ones in terms of signal-to-noise ratio, stability, repeatability, and working life. after 21-day storage, the electrode retained more than 90% of its initial response, indicating that surface modification of gmc with hydrophilic and biocompatible aails could significantly prolong the life of tyrosinase in vitro. the gmc10emim[ala]-based biosensor demonstrates a linear response for phenol concentrations from 0.1 to 10 mu mol?l-1 with a low detection limit of 20 nmol?l-1 and sensitivity of 1385 ma?cm-2?m-1. the gmcaail nanocomposite proves to be a promising platform for enzyme-based biosensors and biocatalysis. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, multidisciplinary |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | physicochemical properties ; fabrication ; electrodes ; tyrosinase ; catalysis ; phenol |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000310074200008 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/143004]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Lidong,Lu, Xianbo,Zhang, Haijun,et al. Amino Acid Ionic Liquid Modified Mesoporous Carbon: A Tailor-made Nanostructure Biosensing Platform[J]. chemsuschem,2012,5(10):1918-1925. |
| APA | Wu, Lidong,Lu, Xianbo,Zhang, Haijun,&Chen, Jiping.(2012).Amino Acid Ionic Liquid Modified Mesoporous Carbon: A Tailor-made Nanostructure Biosensing Platform.chemsuschem,5(10),1918-1925. |
| MLA | Wu, Lidong,et al."Amino Acid Ionic Liquid Modified Mesoporous Carbon: A Tailor-made Nanostructure Biosensing Platform".chemsuschem 5.10(2012):1918-1925. |
入库方式： OAI收割
来源：大连化学物理研究所
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