Ionic liquid-based zwitterionic organic polymer monolithic column for capillary hydrophilic interaction chromatography
文献类型：期刊论文
| 作者 | Wang, Tingting1; Chen, Yihui2; Ma, Junfeng3; Zhang, Xiaodan4; Zhang, Lihua4; Zhang, Yukui4 |
| 刊名 | analyst
 |
| 出版日期 | 2015 |
| 卷号 | 140期号:16页码:5585-5592 |
| 通讯作者 | 王婷婷 |
| 英文摘要 | in the current study, a novel ionic liquid-based zwitterionic organic polymer monolithic column was developed by copolymerizing 1-vinyl-3-(butyl-4-sulfonate) imidazolium, acrylamide and n,n'-methylenebisacrylamide in a quaternary porogenic solvent consisting of formamide, dimethyl sulphoxide, polyethylene glycol 8000 and polyethylene glycol 10 000 for capillary hydrophilic interaction chromatography. the monolithic stationary phase was optimized by adjusting the amount of monomer in the polymerization solution along with the composition of porogenic solvent. the optimized monolith exhibited excellent selectivity and favorable retention for nucleosides and benzoic acid derivatives. the primary factors affecting the separation efficiency of the monolithic column (including acetonitrile content, ph, and buffer salt concentration in the mobile phase) have been thoroughly evaluated. excellent reproducibility of the retention times for five nucleosides was achieved, with relative standard deviations of run-to-run (n = 3), column-to-column (n = 3) and batch-to-batch (n = 3) in the range of 0.18-0.48%, 2.33-4.20% and 3.07-6.50%, respectively. |
| WOS标题词 | science & technology ; physical sciences |
| 学科主题 | 物理化学 |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | stationary phases ; retention behavior ; polar analytes ; ph gradient ; separation ; additives ; cation ; acids ; electrochromatography ; molecules |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000358521400023 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/143698]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Ningbo Univ Technol, Coll Chem Engn, Ningbo 315016, Zhejiang, Peoples R China 2.Xiangshan Entry Exit Inspect & Quarantine, Xiangshan 310014, Peoples R China 3.Johns Hopkins Univ, Sch Med, Dept Biol Chem, Baltimore, MD 21205 USA 4.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Tingting,Chen, Yihui,Ma, Junfeng,et al. Ionic liquid-based zwitterionic organic polymer monolithic column for capillary hydrophilic interaction chromatography[J]. analyst,2015,140(16):5585-5592. |
| APA | Wang, Tingting,Chen, Yihui,Ma, Junfeng,Zhang, Xiaodan,Zhang, Lihua,&Zhang, Yukui.(2015).Ionic liquid-based zwitterionic organic polymer monolithic column for capillary hydrophilic interaction chromatography.analyst,140(16),5585-5592. |
| MLA | Wang, Tingting,et al."Ionic liquid-based zwitterionic organic polymer monolithic column for capillary hydrophilic interaction chromatography".analyst 140.16(2015):5585-5592. |
入库方式： OAI收割
来源：大连化学物理研究所
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