Enhancing the performance of LC-MS for intact protein analysis by counteracting the signal suppression effects of trifluoroacetic acid during electrospray
文献类型：期刊论文
| 作者 | Chen, Jin1,2; Liu, Zheyi1,2; Wang, Fangjun1; Mao, Jiawei1,2; Zhou, Ye1,2; Liu, Jing1,2; Zou, Hanfa1; Zhang, Yukui1 |
| 刊名 | chemical communications
 |
| 出版日期 | 2015 |
| 卷号 | 51期号:79页码:14758-14760 |
| 通讯作者 | fangjunwang ; 邹汉法 |
| 英文摘要 | we develop an acidic vapor assisted electrospray ionization strategy within an enclosed electrospray ionization source to counteract the ion suppression effects caused by trifluoroacetic acid. the mass spectrometry signal intensity of intact proteins was improved 10 times and the number of valid signals for e. coli intact protein samples was improved 96% by using this strategy. |
| 学科主题 | 物理化学 |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, multidisciplinary |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | chromatography-mass-spectrometry ; liquid-chromatography ; mobile-phase ; ionization ; enhancement ; sensitivity ; separation |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000361753000015 |
| 公开日期 | 2015-11-17 |
| 源URL | [http://159.226.238.44/handle/321008/143704]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Jin,Liu, Zheyi,Wang, Fangjun,et al. Enhancing the performance of LC-MS for intact protein analysis by counteracting the signal suppression effects of trifluoroacetic acid during electrospray[J]. chemical communications,2015,51(79):14758-14760. |
| APA | Chen, Jin.,Liu, Zheyi.,Wang, Fangjun.,Mao, Jiawei.,Zhou, Ye.,...&Zhang, Yukui.(2015).Enhancing the performance of LC-MS for intact protein analysis by counteracting the signal suppression effects of trifluoroacetic acid during electrospray.chemical communications,51(79),14758-14760. |
| MLA | Chen, Jin,et al."Enhancing the performance of LC-MS for intact protein analysis by counteracting the signal suppression effects of trifluoroacetic acid during electrospray".chemical communications 51.79(2015):14758-14760. |
入库方式： OAI收割
来源：大连化学物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。