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Surface-Imprinted Nanoparticles Prepared with a His-Tag-Anchored Epitope as the Template

文献类型：期刊论文

作者Li, Senwu1,2; Yang, Kaiguang1; Liu, Jianxi1,2; Jiang, Bo1; Zhang, Lihua1; Zhang, Yukui1
刊名analytical chemistry
出版日期2015-05-05
卷号87期号:9页码:4617-4620
通讯作者张丽华
英文摘要the specific recognition of biomolecules by artificial antibodies has inspired fascination among chemists and biologists. herein, we propose a new method to prepare epitope-oriented surface-imprinted nanoparticles with high template utilization efficiency. using a his-tag as the anchor to facilitate the epitope immobilization/removal and the self-polymerization of dopamine to control the imprinted shell thickness, the prepared epitope-imprinted nanoparticles show specific recognition of the target protein. moreover, with improved hydrophilicity of the his-tag-anchored epitope, this method opens up a universal route for imprinting epitopes with various polarities.
学科主题物理化学
WOS标题词science & technology ; physical sciences
类目[WOS]chemistry, analytical
研究领域[WOS]chemistry
关键词[WOS]silica nanoparticles ; protein recognition ; polymers ; polymerization ; extraction ; separation ; cavities
收录类别SCI
语种英语
WOS记录号WOS:000354153600007
公开日期2015-11-17
源URL[http://159.226.238.44/handle/321008/143715]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714		 Li, Senwu,Yang, Kaiguang,Liu, Jianxi,et al. Surface-Imprinted Nanoparticles Prepared with a His-Tag-Anchored Epitope as the Template[J]. analytical chemistry,2015,87(9):4617-4620.
APA Li, Senwu,Yang, Kaiguang,Liu, Jianxi,Jiang, Bo,Zhang, Lihua,&Zhang, Yukui.(2015).Surface-Imprinted Nanoparticles Prepared with a His-Tag-Anchored Epitope as the Template.analytical chemistry,87(9),4617-4620.
MLA Li, Senwu,et al."Surface-Imprinted Nanoparticles Prepared with a His-Tag-Anchored Epitope as the Template".analytical chemistry 87.9(2015):4617-4620.

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来源：大连化学物理研究所

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