Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus persalinus provides insight into its virulence through horizontal gene transfer
文献类型：期刊论文
| 作者 | Xiong, Jie1; Wang, Guangying1,2; Cheng, Jun1,3; Tian, Miao1,2; Pan, Xuming4; Warren, Alan5; Jiang, Chuanqi1,2; Yuan, Dongxia1; Miao, Wei1 |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2015-10-21 |
| 卷号 | 5 |
| ISSN号 | 2045-2322 |
| 英文摘要 | Certain ciliates of the subclass Scuticociliatia (scuticociliates) are facultative parasites of fishes in which they cause a suite of diseases collectively termed scuticociliatosis. Hitherto, comparatively little was known about genetics and genomics of scuticociliates or the mechanism of scuticociliatosis. In this study, a laboratory culture of the facultatively pathogenic scuticociliate Pseudocohnilembus persalinus was established and its genome sequenced, giving the first genome of a marine ciliate. Genome-wide horizontal gene transfer (HGT) analysis showed P. persalinus has acquired many unique prokaryote-derived genes that potentially contribute to the virulence of this organism, including cell adhesion, hemolysis and heme utilization genes. These findings give new insights into our understanding of the pathology of scuticociliates. |
| WOS标题词 | Science & Technology |
| 类目[WOS] | Multidisciplinary Sciences |
| 研究领域[WOS] | Science & Technology - Other Topics |
| 关键词[WOS] | FLOUNDER PARALICHTHYS-OLIVACEUS ; TURBOT SCOPHTHALMUS-MAXIMUS ; PHOSPHOLIPASE-C ; URONEMA-MARINUM ; PHILASTERIDES-DICENTRARCHI ; RNA-SEQ ; PLASMODIUM-FALCIPARUM ; STAPHYLOCOCCUS-AUREUS ; PROTECTIVE IMMUNITY ; HEMOLYSIN-III |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000363114000001 |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/27278]  |
| 专题 | 水生生物研究所_水生生物分子与细胞生物学研究中心_期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Guangdong Ocean Univ, Zhanjiang 524088, Peoples R China 4.Harbin Normal Univ, Coll Life Sci & Technol, Dept Biol, Lab Protozool, Harbin 150025, Peoples R China 5.Nat Hist Museum, Dept Life Sci, London SW7 5BD, England |
| 推荐引用方式 GB/T 7714 | Xiong, Jie,Wang, Guangying,Cheng, Jun,et al. Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus persalinus provides insight into its virulence through horizontal gene transfer[J]. SCIENTIFIC REPORTS,2015,5. |
| APA | Xiong, Jie.,Wang, Guangying.,Cheng, Jun.,Tian, Miao.,Pan, Xuming.,...&Miao, Wei.(2015).Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus persalinus provides insight into its virulence through horizontal gene transfer.SCIENTIFIC REPORTS,5. |
| MLA | Xiong, Jie,et al."Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus persalinus provides insight into its virulence through horizontal gene transfer".SCIENTIFIC REPORTS 5(2015). |
入库方式： OAI收割
来源：水生生物研究所
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