Measurement of unidirectional P-i to ATP flux in human visual cortex at 7 T by using in vivo P-31 magnetic resonance spectroscopy
文献类型：期刊论文
| 作者 | Lei, H; Ugurbil, K; Chen, W |
| 刊名 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
 |
| 出版日期 | 2003-11-25 |
| 卷号 | 100期号:24页码:14409-14414 |
| 英文摘要 | Taking advantage of the high NMR detection sensitivity and the large chemical shift dispersion offered by ultra-high field strength of 7 T, the effect of magnetization transfer on inorganic phosphate (Pi) resonance during saturation of gamma-ATP resonance, mediated by the ATP synthesis reaction, was observed noninvasively in the human primary visual cortex by using in ViVo P-31 magnetic resonance spectroscopy. The unidirectional flux from P-i to ATIP was measured by using progressive saturation transfer experiments. The cerebral ATP synthesis rate in the human primary visual cortex measured by P-31 magnetic resonance spectroscopy in this study was 12.1 +/- 2.8 mumol ATP/g per min, which agreed well with the value that was calculated indirectly from the cerebral metabolic rate of glucose consumption reported previously. |
| WOS标题词 | Science & Technology |
| 类目[WOS] | Multidisciplinary Sciences |
| 研究领域[WOS] | Science & Technology - Other Topics |
| 关键词[WOS] | SATURATION-TRANSFER MEASUREMENTS ; PHOSPHATE EXCHANGE-REACTIONS ; CREATINE-KINASE REACTION ; ESCHERICHIA-COLI-CELLS ; HUMAN BRAIN ; RAT-HEART ; SACCHAROMYCES-CEREVISIAE ; GLUCOSE-UTILIZATION ; INTACT MYOCARDIUM ; NMR MEASUREMENT |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000186803800117 |
| 公开日期 | 2015-12-08 |
| 源URL | [http://ir.wipm.ac.cn/handle/112942/8853]  |
| 专题 | 武汉物理与数学研究所_2011年以前论文发表（包括2011年） |
| 作者单位 | 1.Univ Minnesota, Sch Med, Ctr Magnet Resonance Res, Dept Radiol, Minneapolis, MN 55455 USA 2.Chinese Acad Sci, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan Inst Phys & Math, Wuhan 430071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lei, H,Ugurbil, K,Chen, W. Measurement of unidirectional P-i to ATP flux in human visual cortex at 7 T by using in vivo P-31 magnetic resonance spectroscopy[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2003,100(24):14409-14414. |
| APA | Lei, H,Ugurbil, K,&Chen, W.(2003).Measurement of unidirectional P-i to ATP flux in human visual cortex at 7 T by using in vivo P-31 magnetic resonance spectroscopy.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,100(24),14409-14414. |
| MLA | Lei, H,et al."Measurement of unidirectional P-i to ATP flux in human visual cortex at 7 T by using in vivo P-31 magnetic resonance spectroscopy".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100.24(2003):14409-14414. |
入库方式： OAI收割
来源：武汉物理与数学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。