Hair Selenium Levels of School Children in Kashin-Beck Disease Endemic Areas in Tibet, China
文献类型：SCI/SSCI论文
| 作者 | Chen Z.; Li, H. R.; Yang, L. S.; Wang, W. Y.; Li, Y. H.; Gong, H. Q.; Guo, M.; Nima, C. J.; Zhao, S. C.; Wang, J. |
| 发表日期 | 2015 |
| 关键词 | Kashin-Beck disease Tibet School children Hair Selenium kaschin-beck trace-elements icp-ms serum plasma cancer foods etiology province copper |
| 英文摘要 | Previous studies have shown that the selenium (Se) deficiency is an important factor for the etiology of Kashin-Beck disease (KBD). Although KBD is presently controlled in most regions of China, it is still active in the Tibetan Plateau. The present study aimed to assess the nutritional status of selenium in school children by using the Se level in hair as a biomarker in KBD endemic areas of Lhasa in Tibet, China. Hair samples of 155 school children aged 6-15 years were collected in both KBD areas and non-KBD areas of Lhasa in 2013. The Se level in the hair samples was determined by inductive coupled plasma mass spectrometry (ICP-MS). The average concentration of Se in children's hair was 0.232 mu g/g in KBD areas of Lhasa, which was significantly higher than the data reported decades ago. A significant difference in hair Se was observed between the boys (0.255 mu g/g) and the girls (0.222 mu g/g) in the studied KBD areas (P < 0.01, Mann-Whitney U test), but hair Se did not vary by age or region. School children in KBD endemic areas in Lhasa likely have improved Se status as a result of high Se content staple food substitution with the enforcement of Free Education Policy and Nutrition Improvement Plan in Tibet. Nevertheless, there were still 20.3 % of students with low Se status (hair Se < 0.20 mu g/g), which showed that Se status of school children was also partly affected by low Se environment in KBD endemic areas of Lhasa. |
| 出处 | Biological Trace Element Research |
| 卷 | 168 |
| 期 | 1 |
| 页 | 25-32 |
| 收录类别 | SCI |
| 语种 | 英语 |
| ISSN号 | 0163-4984 |
| 源URL | [http://ir.igsnrr.ac.cn/handle/311030/38568]  |
| 专题 | 地理科学与资源研究所_历年回溯文献 |
| 推荐引用方式 GB/T 7714 | Chen Z.,Li, H. R.,Yang, L. S.,et al. Hair Selenium Levels of School Children in Kashin-Beck Disease Endemic Areas in Tibet, China. 2015. |
入库方式： OAI收割
来源：地理科学与资源研究所
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