Chiral primary amine catalysed asymmetric conjugate addition of azoles to alpha-substituted vinyl ketones
文献类型：期刊论文
| 作者 | Fu, Niankai1,2; Zhang, Long1,2,3; Luo, Sanzhong1,2,3; Cheng, Jin-Pei1,2,3 |
| 刊名 | Organic Chemistry Frontiers
 |
| 出版日期 | 2014 |
| 卷号 | 1期号:1页码:68-72 |
| 英文摘要 | We report here the first effective example of asymmetric conjugate addition-protonation reactions of azoles to vinyl ketones by chiral primary amine catalysis. High enantioselectivity can be easily achieved by screening different primary amine catalysts, and the Curtin-Hammett control in the C-N bond formation step was verified by DFT calculations to account for the observed stereoselectivity. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2015-12-22 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/29219]  |
| 专题 | 化学研究所_分子识别与功能实验室 |
| 作者单位 | 1.Chinese Acad Sci, BNLMS, CAS Key Lab Mol Recognit, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Funct Inst Chem, Beijing 100190, Peoples R China 3.Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fu, Niankai,Zhang, Long,Luo, Sanzhong,et al. Chiral primary amine catalysed asymmetric conjugate addition of azoles to alpha-substituted vinyl ketones[J]. Organic Chemistry Frontiers,2014,1(1):68-72. |
| APA | Fu, Niankai,Zhang, Long,Luo, Sanzhong,&Cheng, Jin-Pei.(2014).Chiral primary amine catalysed asymmetric conjugate addition of azoles to alpha-substituted vinyl ketones.Organic Chemistry Frontiers,1(1),68-72. |
| MLA | Fu, Niankai,et al."Chiral primary amine catalysed asymmetric conjugate addition of azoles to alpha-substituted vinyl ketones".Organic Chemistry Frontiers 1.1(2014):68-72. |
入库方式： OAI收割
来源：化学研究所
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