中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [37]
采集方式
OAI收割 [37]
内容类型
期刊论文 [37]
发表日期
2017 [37]
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共37条,第1-10条
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存缴方式:oaiharvest
发表日期:2017
内容类型:期刊论文
专题:上海药物研究所
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Benzo[c][1,2,5] thiadiazole derivatives: A new class of potent Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5154-5157
作者:
Wang, Wen-Long
;
Chen, Xiao-Yu
;
Gao, Ya
;
Gao, Li-Xin
;
Sheng, Li
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Benzo[c][1,2,5] thiadiazole derivatives
PTP1B
SHP2
Inhibitors
Structure-activity relationships (SAR)
Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 卷号: 15, 期号: 44, 页码: 9352-9361
作者:
Jiang, Hao
;
Xing, Jing
;
Wang, Chen
;
Zhang, Hao
;
Yue, Liyan
  |  
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2019/01/08
Label-free brainwide visualization of senile plaque using cryo-micro-optical sectioning tomography
期刊论文
OAI收割
OPTICS LETTERS, 2017, 卷号: 42, 期号: 21, 页码: 4247-4250
作者:
Luo, Yilin
;
Wang, Anle
;
Liu, Mengmeng
;
Lei, Tian
;
Zhang, Xiaochuan
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Src-dependent phosphorylation of mu-opioid receptor at Tyr(336) modulates opiate withdrawal
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2017, 卷号: 9, 期号: 11, 页码: 1521-1536
作者:
Zhang, Lei
;
Kibaly, Cherkaouia
;
Wang, Yu-Jun
;
Xu, Chi
;
Song, Kyu Young
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
lentivirus injection
locus coeruleus
naloxone-precipitated opiate withdrawal
opiate addiction
Src-mediated phosphorylation of MOR at Tyr(336)
Discovery of cycloalkyl-fused N-thiazol-2-yl-benzamides as tissue non-specific glucokinase activators: Design, synthesis, and biological evaluation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 页码: 128-152
作者:
Wang, Zhengyu
;
Shi, Xiaofan
;
Zhang, Huan
;
Yu, Liang
;
Cheng, Yanhua
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Type 2 diabetes mellitus
Hypoglycemia
Dyslipidemia
Glucokinase activators
N-Thiazol-2-yl-benzamides
Synthesis and biological evaluation of benzothiazol-based 1,3,4-oxadiazole derivatives as amyloid beta-targeted compounds against Alzheimer's disease
期刊论文
OAI收割
MONATSHEFTE FUR CHEMIE, 2017, 卷号: 148, 期号: 10, 页码: 1807-1815
作者:
Mei, Wen-wen
;
Ji, Sha-sha
;
Xiao, Wei
;
Wang, Xue-dong
;
Jiang, Cheng-shi
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/01/08
Structure-activity relationships
Heterocycles
Drug research
Neuroprotective effects
Cyanobacterial peptides as a prototype for the design of cathepsin D inhibitors
期刊论文
OAI收割
JOURNAL OF PEPTIDE SCIENCE, 2017, 卷号: 23, 期号: 9, 页码: 701-706
作者:
Xu, Hao
;
Bao, Keting
;
Tang, Shuai
;
Ai, Jing
;
Hu, Haiyan
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
cathepsin D
inhibitor
peptides
structural modification
transition-state mimics
Cytotoxic cassane diterpenoids from the seeds of Caesalpinia sappan
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2017, 卷号: 28, 期号: 8, 页码: 1711-1715
作者:
Wu, Zheng-Feng
;
Bao, Han
;
Zhou, Fa-Yang
;
Liu, Jing-Xin
;
Meng, Fan-Cheng
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Caesalpinia sappan
Cassane diterpenoid
Phanginin
Caesalsappanin
Cytotoxicity
Multiple Dose Pharmacokinetics and Safety of Sulcardine Sulfate in Healthy Chinese Male Subjects: An Open-Label Phase I Clinical Study
期刊论文
OAI收割
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2017, 卷号: 42, 期号: 4, 页码: 593-599
作者:
Wang, Wei
;
Qian, Hong-jie
;
Xin, Liang
;
Zhang, Meng-qi
;
Lu, Dong-ying
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
The Small GTPase Rac1 Contributes to Extinction of Aversive Memories of Drug Withdrawal by Facilitating GABA(A) Receptor Endocytosis in the vmPFC
期刊论文
OAI收割
JOURNAL OF NEUROSCIENCE, 2017, 卷号: 37, 期号: 30, 页码: 7096-7110
作者:
Wang, Weisheng
;
Ju, Yun-Yue
;
Zhou, Qi-Xin
;
Tang, Jian-Xin
;
Li, Meng
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
aversive memory
drug withdrawal
endocytosis
extinction
GABA(A) receptor
Rac1