机构

• 上海药物研究所 [4]
• 上海生物化学与细胞生... [2]
• 昆明植物研究所 [1]
• 上海应用物理研究所 [1]
• 中国科学院大学 [1]

采集方式

• OAI收割 [8]
• iSwitch采集 [1]

内容类型

• 期刊论文 [9]

发表日期

• 2023 [1]
• 2019 [1]
• 2018 [1]
• 2017 [1]
• 2015 [1]
• 2012 [2]
• 更多

学科主题

• Research &... [1]

筛选

浏览/检索结果: 共9条，第1-9条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120 作者:  Zhou,Gui-Feng;  Tang,Jing;  Ma,Yuan-Lin;  Fu,Xian;  Liu,Jun-Yan   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/09 conophylline  ARL6IP1  5'UTR  FXR1  BACE1 translation  AMYLOID PRECURSOR PROTEIN  A-BETA  TRANSGENIC MICE  MOUSE MODEL  NEURODEGENERATION  EXPRESSION  REDUCTION  MEMBRANE  MEMORY  ER   Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 10, 页码: 4303-4318 作者:  Chen, Jianzhong;  Wang, Jinan;  Yin, Baohua;  Pang, Laixue;  Wang, Wei   |  收藏  |  浏览/下载：95/0  |  提交时间：2020/07/01 beta-amyloid cleaving enzyme  binding selectivity  MSMD  hierarchical clustering analysis  MM-GBSA   Visualization of Alzheimer's Disease Related alpha-/beta-/gamma-Secretase Ternary Complex by Bimolecular Fluorescence Complementation Based Fluorescence Resonance Energy Transfer 期刊论文  OAI收割 FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11, 期号: 1, 页码: 431 作者:  Wang, Xin;  Pei, Gang   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/04/28 Amyloid Precursor Protein  Beta-secretase  App  Site  Cleavage  Adam10  Bace1  Localization  Dimerization  Endocytosis   Synthetic Analogues of Betulinic Acid as Potent Inhibitors of PS1/BACE1 Interaction to Reduce A Generation 期刊论文  OAI收割 CHINESE JOURNAL OF CHEMISTRY, 2017, 卷号: 35, 期号: 1, 页码: 103-112 作者:  Zhang, Chenlu;  Wang, Xiaoyin;  Cui, Jin;  Li, Xiaohang;  Zhang, Yangming   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Alzheimer's disease  PS1  BACE1 interaction  A  betulinic acid  SAR   Targeting the gamma-/beta-secretase interaction reduces beta-amyloid generation and ameliorates Alzheimer's disease-related pathogenesis 期刊论文  OAI收割 CELL DISCOVERY, 2015, 卷号: 1 作者:  Cui, Jin;  Wang, Xiaoyin;  Li, Xiaohang;  Wang, Xin;  Zhang, Chenlu   |  收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 PS1/BACE1 interaction  A beta generation  Alzheimer's disease   Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations 期刊论文  OAI收割 ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 2012, 卷号: 68 Xu, YC; Li, MJ; Greenblatt, H; Chen, WY; Paz, A; Dym, O; Peleg, Y; Chen, TT; Shen, X; He, JH（何建华）; Jiang, HL; Silman, I; Sussman, JL 收藏  |  浏览/下载：19/0  |  提交时间：2013/12/05 Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations 期刊论文  OAI收割 ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 2012, 卷号: 68, 页码: 13-25 作者:  Xu, Yechun;  Li, Min-jun;  Greenblatt, Harry;  Chen, Wuyan;  Paz, Aviv   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 The enhancement of amyloid precursor protein and beta-site amyloid cleavage enzyme 1 interaction: Amyloid-beta production with aging 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2010, 卷号: 25, 期号: 3, 页码: 401-407 作者:  Zou, L;  Yang, RX;  Zhang, PH;  Da, Y 收藏  |  浏览/下载：12/0  |  提交时间：2015/07/22 amyloid precursor protein  beta-site amyloid cleavage enzyme 1  amyloid-beta  aging  interaction   Genetic association of bace1 gene polymorphism c786g with late-onset alzheimer's disease in chinese 期刊论文  iSwitch采集 Journal of molecular neuroscience, 2005, 卷号: 25, 期号: 2, 页码: 127-131 作者:  Kan, R;  Wang, BB;  Zhang, CF;  Jin, F;  Yang, Z 收藏  |  浏览/下载：21/0  |  提交时间：2019/05/10 Load  A beta peptides  Bace1  Apoe  Polymorphism  Chinese