中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
计算技术研究所 [1]
上海生物化学与细胞生... [1]
采集方式
OAI收割 [7]
内容类型
期刊论文 [7]
发表日期
2024 [1]
2023 [1]
2021 [3]
2010 [1]
2009 [1]
学科主题
Biochemist... [1]
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浏览/检索结果:
共7条,第1-7条
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Optical Genome Mapping Reveals the Landscape of Structural Variations and Their Clinical Significance in HBOC-Related Breast Cancer
期刊论文
OAI收割
FRONTIERS IN BIOSCIENCE-LANDMARK, 2024, 卷号: 29, 期号: 1, 页码: 1-15
作者:
Cheng, Yanan
;
Dong, Li
;
Bu, Dechao
;
Han, Lei
;
Zhao, Yi
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/20
HBOC
breast cancer
optical genome mapping
structural variation
BRCA1/2
chromothripsis
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:
Wang, Li-Min
;
Wang, Pingyuan
;
Chen, Xiao-Min
;
Yang, Hui
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
homologous recombination repair
olaparib-resistant
PARP inhibitor
PARP7
type I interferons
Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers
期刊论文
OAI收割
INVESTIGATIONAL NEW DRUGS, 2021, 页码: 9
作者:
Li, Meng-Zhu
;
Meng, Tao
;
Song, Shan-Shan
;
Bao, Xu-Bin
;
Ma, Lan-Ping
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
G-quadruplex stabilizer
MTR-106
BRCA-deficiency
PARP inhibitor
DNA damage
Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer
期刊论文
OAI收割
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18
作者:
Zhang, Ning
;
Tian, Yu-Nan
;
Zhou, Li-Na
;
Li, Meng-Zhu
;
Chen, Hua-Dong
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/05/24
Glycogen synthase kinase 3β inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer
期刊论文
OAI收割
Cell Death & Disease, 2021, 卷号: 12, 期号: 2, 页码: 1
作者:
Ning Zhang
;
Yu-Nan Tian
;
Li-Na Zhou
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/12/01
Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2010, 卷号: 31, 期号: 9, 页码: 1172-1180
作者:
He, Jin-xue
;
Yang, Chun-hao
;
Miao, Ze-hong
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
poly(ADP-ribose) polymerase inhibitor
DNA repair
BRCA1/2
anticancer agents
homologous recombination
BRCA1 Interaction of Centrosomal Protein Nlp Is Required for Successful Mitotic Progression
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 卷号: 284, 期号: 34, 页码: 22970-22977
作者:
Jin, SQ
;
Gao, H
;
Mazzacurati, L
;
Wang, Y
;
Fan, WH
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2015/07/22